Adult and elderly Lifelines participants participating in the second general assessment 2A received two questionnaires, 2A Questionnaire 1 and 2A Questionnaire 2.
2A Q1 was followed by 2A Visit 1, on average within xx days (+/- yy days).
2A Q1 was also followed by 2A Questionnaire 2, on average within xx weeks (+/- yy weeks).
2A Q1 was followed up by assessment 2B, on average within xx months (+/1 yy months).
2A Q1 is procedurally equivalent to 1A Questionnaire 1 and 3A Questionnaire 1.
The average time between 1A Questionnaire 1 and 2A Q1 was xx months (+/- yy months).

Of all participants that filled out 2A Q1 (n = ~100,000), 36% of participants filled in a paper variant whereas 64% filled in a digital variant.

2A Q1 contained the following sections and subsections:

• Personal data
• Education
• Family composition
• Family deaths
• Household composition
• Profession
• Employment status

• Cancer
• Cardiovascular diseases
• Diabetes
• Digestive diseases
• Diseases (other)
• Fatigue (general)
• Kidney/bladder diseases
• Mental illnesses
• Musculoskeletal conditions
• Neurological disorders
• Respiratory diseases
• Symptoms (SCL-90)

• Independence

• Home environment (general)
• Physical activity (SQUASH)

• Medication
• Surgery
• Treatment (general)

• Stress (LDI)
• Stress (LTE)

NB: The three FFQ petals (1/2/3) were distributed over three questionnaires (1B, 1C and 2A Q1), so that each participant received the petals in one of six possible orders ([1-2-3], [1-3-2], [2-1-3], [2-3-1], [3-1-2], or [3-2-1]).

• Macronutrients (FFQ-h)
• Petal 1 (FFQ1)
• Petal 2 (FFQ2)
• Petal 3 (FFQ3)

• Anthropometry (self-reported)

• Quality of Life (RAND)