Adult and elderly Lifelines participants participating in general assessment 1A (“Baseline”) received two follow-up questionnaires, 1B and 1C.
1C was sent out on average 28 months (SD ± 10 months) after 1A Questionnaire 2.
1C was sent out on average 12 months (SD ± 3 months) after 1B.
1C was followed by 2A Questionnaire 1 after on average 16 months (± 10 months).

Of all participants that filled out 1C (n = ~100,000), 33% of participants filled in a paper variant whereas 66% filled in a digital variant.

1C contained the following sections and subsections:

• Education
• Family composition
• Family deaths
• Household composition
• Personal data
• Profession
• Occupational history
• Employment status

• Bronchial Hyperresponsiveness (BHQ)
• Cancer
• Cardiovascular diseases
• Connective Tissue Disease (CSQ)
• Diabetes
• Digestive system diseases
• Diseases (other)
• Fatigue (general)
• Kidney & bladder diseases
• Mental illnesses
• Musculoskeletal conditions
• Neurological disorders
• Respiratory diseases
• Symptoms (SCL-90)

NB: Only elderly participants (65+) were asked these questions

• Independence

• Exposure to noise (subjective)
• Exposure to radiation
• Home environment (general)
• Informal care
• Physical activity (SQUASH) - 1 general question
• Physical activity (general)
• Sleepiness (ESS)
• Smoking & tobacco use
• Volunteer work (general)

• Hospitalization
• Medication
• Surgery
• Treatment (general)

• Personality (GAS)
• Personality (Type D)
• Stress (LDI)
• Stress (LTE)

NB: The three FFQ petals (1/2/3) were distributed over three questionnaires (1B, 1C and 2A Questionnaire 1), so that each participant received the petals in one of six possible orders ([1-2-3], [1-3-2], [2-1-3], [2-3-1], [3-1-2], or [3-2-1]).

• Macronutrients (FFQ-h)
• Petal 1 (FFQ1)
• Petal 2 (FFQ2)
• Petal 3 (FFQ3)

• Anthropometry (self-reported)

• Quality of Life (RAND)
• Self-management (SMAS)
• Work psychology (general)
• Work ability (WAI)
• Psychosocial work environment (COPSOQ)