BIONIC is the name of an additional assessment in Lifelines.
It was performed in collaboration with the Dutch BIONIC consortium and with the University Center of Psychiatry in Groningen.
The goal of BIOQ was to assess lifetime depression (in DEPQ and DEAQ) & generalized anxiety disorder (in DEAQ) in Lifelines participants by implementation of the Lifetime Depression Assessment Self-Report (LIDAS) digital questionnaire plus some additional questions.
Note that current depression & anxiety of Lifelines participants were assessed in general assessments 1A, 2A and 3A using the MINI Neuropsychiatric Interview.

BIOQ was executed in two time periods: in 2016 and 2018.

• For DEPQ (2016), the LIDAS was sent to all adult participants with a known e-mail address in the GWAS subcohort (n=~10.000). ~5500 participants (50%) filled in the questionnaire. ^{1) 2)}
  
• For DEAQ (2018) (in collaboration with the University Center of Psychiatry at the UMCG), the LIDAS plus some additional questions was sent to all adult participants with a known e-mail address in the entire cohort (n=133.000). ~43.500 participants (36%) filled in the questionnaire ³⁾.

The BIOQ variables can be found on the DEPQ and DEAQ pages.

This project was funded by the Dutch research infrastructure for biobanking (BBMRI-NL) as Rainbow project Phenomics 2.0 – proof of principle for major depressive disorder (RP-12).