The Skin Conditions questionnaire is an additional assessment among adult Lifelines participants. The digital questionnaire was developed at the initiative of the UMCG Department of Dermatology (NL). With the aim of the questionnaire being to gain more insight into hidradentitis supperativa and eczema in the general population.

The collected SKIQ data is currently still under embargo. Please contact the Lifelines data managers at data@lifelines.nl for more information.

When the SKIQ data has been used in your research, you will have to include the following references:

• for publication on hand eczema: Voorberg, A.N. et al. (2022) Prevalence and Severity of Hand Eczema in the Dutch General Population: A Cross-sectional, Questionnaire Study within the Lifelines Cohort Study, Acta Derm Venereol 102
• for publications on atopic dermatitis/eczema: Zhang, J et al. (2021) Prevalence of adult atopic dermatitis in the general population, with a focus on moderate to severe disease: results from the Lifelines Cohort Study. Eur Acad Dermatol Venereol 35(11):e787-e790

The digital questionnaire was sent out between February and May 2020.
~136,000 adult Lifelines participants received the questionnaire, of which ~58,000 participants (43%) responded.

The questions included in the skin conditions questionnaire included items from the following subsections:

• Acne (8 items)
• Allergies (2 items)
• Eczema measure (POEM) (8 items)
• Familial diseases (other) (1 item)
• Medication (15 items)
• Occupational eczema (NOSQ) (52 items)
• Skin conditions (96 items)
• Treatment (general) (28 items)

• Zhang, J et al. (2021) Prevalence of adult atopic dermatitis in the general population, with a focus on moderate to severe disease: results from the Lifelines Cohort Study. Eur Acad Dermatol Venereol 35(11):e787-e790
• * Zhang J et al. (2021) Impact of the COVID-19 pandemic on adults with moderate-to-severe atopic dermatitis in the Dutch general population JAAD Int 6:86-93
• Zhang, J et al. (2022) Moderate-to-severe atopic dermatitis and lifestyle factors in the Dutch general population. Clin Exp Dermatol 47(8): 1523–1535
• Voorberg, A.N. et al. (2022) Prevalence and Severity of Hand Eczema in the Dutch General Population: A Cross-sectional, Questionnaire Study within the Lifelines Cohort Study, Acta Derm Venereol 102.
• Loman L. and Schuttelaar M.L.A. (2022) Hand eczema and lifestyle factors in the Dutch general population: Evidence for smoking, chronic stress, and obesity. Contact Dermatitis 86(2):80-88.
• Brands M.J. et al. (2022) Exposure and work-related factors in subjects with hand eczema: Data from a cross-sectional questionnaire within the Lifelines Cohort Study. Contact Dermatitis 86(6):493-506
• Prens L.M. et al. (2022) New insights in hidradenitis suppurativa from a population-based Dutch cohort: prevalence, smoking behaviour, socioeconomic status and comorbidities Br J Derm 186(5): 814–822
• Zhang J et al. (2023) Limited health literacy and its associated health outcomes among adults with at least 2 atopic diseases J Allerg Clin Immunol 11(5): 1429-1438
• Zhang J et al. (2023) Beyond anxiety and depression: Loneliness and psychiatric disorders in adults with atopic dermatitis ActaDV 103, adv9378
• van der Weijden DAY (2023) Hidradenitis suppurativa tarda: defining an understudied elderly population Br J Derm: ljad317
• Brands M. J. et al. (2024) Hand eczema-related presenteeism and sickness absence: A cross-sectional population-based study. Contact Dermatitis 90(4):372-377