Table of Contents
Memory and Cognition Test (MCOT)
MCOT is the name of an additional assessment in which a memory and cognition test is performed via a smartphone app, in a subgroup of adult Lifelines participants. Implementation of this additional study in Lifelines was initiated by the department of Nephrology of the University Medical Center Groningen. The purpose of this study was to determine reference values for the digital version of the test, since they may differ from the available reference values that are based on the paper version.
The collected MCOT data is currently under embargo. Please contact the Lifelines data managers at data@lifelines.nl for more information.
Protocol
Invitations were sent in December 2025. Non-responders received a personal reminder after ~3 weeks. Invited participants could download the app and perform the test until January 21st 2026.
The test that was used in the MCOT study, was a digital version of the Symbol Digit Modalities Test (SDMT). During the 90-second digital SDMT task, individuals were presented with a set of symbols and asked to identify the correct number associated with each one.
Response
~25,000 participants (18+) were invited for MCOT. The response rate was 26% (n=~6,500).
Variables
| Label English | Label Dutch | Code | Variable | Assessment | Age |
| number of attempts on sdmt test | aantal pogingen op sdmt test | sdmt_attempts_adu_m_1 | number_attempts_test | MCOT | 18+ |
| number of correct answers on sdmt test | aantal goede antwoorden op sdmt test | sdmt_correct_adu_m_1 | correct_answers_test | MCOT | 18+ |
| device model and android version | apparaat model en android versie | sdmt_device_adu_m_1 (IO) | sdmt_device | MCOT | 18+ |
| participant notes in sdmt test | deelnemer notities in sdmt test | sdmt_notes_adu_m_1 (IO) | patientnotes | MCOT | 18+ |
| time at which participant performed the sdmt test | tijd waarop de deelnemer de sdmt test deed | sdmt_time_adu_m_1 | sdmt_time | MCOT | 18+ |