Big Data is the name of an additional questionnaire performed in collaboration with the department of epidemiology at the UMC Groningen, aimed to acquire insights into the differences between participants and refusers of participation in a Dutch population-based biobank (i.e., Lifelines).

When the BIGQ data has been used in your research, you will have to include the following references:

• Motives for withdrawal of participation in biobanking and participants’ willingness to allow linkages of their data Broekstra, R. , Aris-Meijer, J. , Maeckelberghe, E. L. M. , Stolk, R. & Otten, S. , mrt-2022 , In: European Journal of Human Genetics. 30 , 367–377
• Demographic and prosocial intrapersonal characteristics of biobank participants and refusers: the findings of a survey in the Netherlands Broekstra, R. , Aris-Meijer, J. , Maeckelberghe, E. , Stolk, R. & Otten, S. , jan-2021 , In: EJHG. 1 , 11-19

In March - May 2018, Lifelines invited ~7,000 adult participants to participate in the additional digital questionnaire.
~2,200 participants responded (31,4%).

• Broekstra, R. et al. (2021) Demographic and prosocial intrapersonal characteristics of biobank participants and refusers: the findings of a survey in the Netherlands. Eur J Human Gen 29:11–19.
• Broekstra, R. et al. (2021) Motives for withdrawal of participation in biobanking and participants' willingness to allow linkages of their data. Eur J Human Gen, in press.

The following variables were collected: