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mini_mental_state_examination

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Mini Mental State Examination (MMSE)

The Mini International Neuropsychiatric Interview (MINI) (section: mental health) was measured in all elderly Lifelines participants during:

Background

The Mini Mental State Examination (MMSE) is a brief cognition test used to assess cognitive impairments (section: mental health). It is commonly used in medicine and allied health to screen for dementia.
The MMSE was performed in ca. 12.000 elderly (65+) participants during 1A Visit 1. ~12% scored below 24 points (NB: in case of an MMSE score <26 at 1A visit 1, the Proxy interview was performed on location).
The MMSE is implemented again in 3A Visit 1 and 4A Visit 1.
The MMSE is used in conjunction with other cognition tests in Lifelines, i.e. the RFFT (also during 1A Visit 1, 3A Visit 1, and 4A Visit 1), and the CogState (during 2A visit 1, 3A Visit 1, and 4A Visit 1). The MMSE should not be confused with the Mini Neuropsychiatric Interview, which is also used in Lifelines but assesses anxiety and depression.

De MMSE includes simple questions and tasks in a number of areas:

  • orientation (V1a-e, V2a-e, max. 10 points);
  • registration (V3, max. 3 points);
  • attention and calculation (V4, max. 5 points);
  • recall (V5, max. 3 points);
  • language (V6-10, max. 8 points);
  • basic motor skills (V11, max. 1 point, copy a drawing of two pentagons as shown in figure).

Scoring

A total of 30 points can be scored in the MMSE (see English protocol for details on scoring). The final score will give a first indication of the presence and level of cognitive impairment (but note that the MMSE is not a diagnostic instrument).

  • 24-30 points: No cognitive impairment
  • 18-23 points: Mild to moderate cognitive impairment
  • 0-17 points: Severe cognitive impairment

Note that in Lifelines, the computer programme gave the following raw data scores:

  • 12 out of 30 items were scored as 1 for correct and 0 for incorrect
  • 18 out of 30 items were scored as 2 for correct and 1 for incorrect

The programme therefore subtracted 1 from each score in these 18 items to get the final score.
When raw MMSE data are used for calculations, the same subtraction should be made.
The Lifelines protocol of the MMSE (in Dutch) can be downloaded here: mmse_in_dutch.pdf
The English equivalent can be downloaded here: mmse_in_english.pdf

Variables

Variables

Label English Label Dutch Code Variable Assessment Age IO
what year is it? welk jaar is het? mmse_time_adu_m_01_a v1a 1A 3A 4A 65+
what season is it? welk seizoen is het? mmse_time_adu_m_01_b v1b 1A 3A 4A 65+
which month of the year is it? welke maand van het jaar is het? mmse_time_adu_m_01_c v1c 1A 3A 4A 65+
what is today's date? wat is de datum van vandaag? mmse_time_adu_m_01_d v1d 1A 3A 4A 65+
what day of the week is it today? welke dag van de week is het? mmse_time_adu_m_01_e v1e 1A 3A 4A 65+
in which province are we now? in welke provincie zijn we nu? mmse_place_adu_m_02_a v2a 1A 3A 4A 65+
in what city or town are we now? in welke plaats zijn we nu? mmse_place_adu_m_02_b v2b 1A 3A 4A 65+
in what street are we now? in welke straat zijn we nu? mmse_place_adu_m_02_c v2c 1A 3A 4A 65+
what is this building called? hoe heet dit gebouw? mmse_place_adu_m_02_d v2d 1A 3A 4A 65+
on what floor are we now? op welke verdieping zijn we nu? mmse_place_adu_m_02_e v2e 1A 3A 4A 65+
apple / i will name three objects now. could you repeat them after i've said all three? appel / ik noem nu drie voorwerpen. wilt u die herhalen nadat ik ze alle drie gezegd heb? mmse_object_adu_m_03_a v3a 1A 65+
key / i will name three objects now. could you repeat them after i've said all three? sleutel / ik noem nu drie voorwerpen. wilt u die herhalen nadat ik ze alle drie gezegd heb? mmse_object_adu_m_03_b v3b 1A 65+
table / i will name three objects now. could you repeat them after i've said all three? tafel / ik noem nu drie voorwerpen. wilt u die herhalen nadat ik ze alle drie gezegd heb? mmse_object_adu_m_03_c v3c 1A 65+
score from the three objects / i will name three objects. could you repeat them after i said them all? remember them, because i will ask you to recall them in a few minutes. score van de drie voorwerpen / ik noem nu drie voorwerpen. wilt u die herhalen nadat ik ze alle drie gezegd heb? onthoud ze want ik vraag u over enkele minuten ze opnieuw te noemen. mmse_objectscore_adu_m_03 v3 3A 4A 65+
i will name three objects. could you repeat them after i said them all? remember them, because i will ask you to recall them in a few minutes. ik noem nu drie voorwerpen. wilt u die herhalen nadat ik ze alle drie gezegd heb? onthoud ze want ik vraag u over enkele minuten ze opnieuw te noemen. mmse_object_adu_m_03 v3_original 3A 4A 65+
could you subtract seven from 100 and subtract seven again from that number and keep going like that? (score: 0-5 points) wilt u van de 100 zeven aftrekken en van wat overblijft weer zeven aftrekken en zo doorgaan? (score: 0-5 punten) mmse_calculation_adu_m_04 v4 1A 65+
calculation test (subtract in steps of 7) rekentest (telkens 7 aftrekken) mmse_calculation_adu_m_04_a v4a_original 3A 4A 65+
score from calculation test / subtract in steps of 7 score van de rekentest / telkens 7 aftrekken mmse_calculationscore_adu_m_04_a v4a 3A 4A 65+
spelling test (spell 'worst' backward) spellingtest ('worst' achterstevoren spellen) mmse_spelling_adu_m_04_b v4b_original 3A 4A 65+
score from the spelling test / spell 'worst' backward score van de spellingtest / 'worst' achterstevoren spellen mmse_spellingscore_adu_m_04_b v4b 3A 4A 65+
apple / could you mention again the three objects i just named? appel / noemt u nogmaals de drie voorwerpen van zojuist. mmse_recall_adu_m_05_a v5a 1A 65+
key / could you mention again the three objects i just named? sleutel / noemt u nogmaals de drie voorwerpen van zojuist. mmse_recall_adu_m_05_b v5b 1A 65+
table / could you mention again the three objects i just named? tafel / noemt u nogmaals de drie voorwerpen van zojuist. mmse_recall_adu_m_05_c v5c 1A 65+
name the three objects from before noemt u nogmaals de drie voorwerpen van zojuist mmse_recall_adu_m_05 v5_original 3A 4A 65+
score from the recall test / name the three objects from before score van de geheugentest / noemt u nogmaals de drie voorwerpen van zojuist mmse_recallscore_adu_m_05 v5 3A 4A 65+
mini_mental_state_examination.1789571344.txt.gz · Last modified: by simone