cohort
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cohort [2020/06/05 09:22] trynke |
cohort [2024/05/16 12:29] (current) trynke |
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| ====== General Cohort & Factsheets ====== | ====== General Cohort & Factsheets ====== | ||
| - | The general cohort of [[Start|Lifelines]] consists of 167.729 participants, identified with a Lifelines-ID.\\ | + | The general population cohort of [[Start|Lifelines]] consists of 167.729 participants, identified with a Lifelines-ID.\\ |
| ===== Recruitment ===== | ===== Recruitment ===== | ||
| Lifelines participants were initially recruited through general practitioners in the three provinces in the [[location|northern part of the Netherlands]]: Groningen, Friesland and Drenthe((Scholtens, S., Smidt, N., Swertz, M.A., Bakker, S.J.L., Dotinga, A., Vonk, J.M., van Dijk, F., van Zon, S.K.R., Wijmenga, C., Wolffenbuttel, B.H.R., et al. (2015). Cohort Profile: LifeLines, a three-generation cohort study and biobank. Int. J. Epidemiol. 44, 1172–1180)).\\ | Lifelines participants were initially recruited through general practitioners in the three provinces in the [[location|northern part of the Netherlands]]: Groningen, Friesland and Drenthe((Scholtens, S., Smidt, N., Swertz, M.A., Bakker, S.J.L., Dotinga, A., Vonk, J.M., van Dijk, F., van Zon, S.K.R., Wijmenga, C., Wolffenbuttel, B.H.R., et al. (2015). Cohort Profile: LifeLines, a three-generation cohort study and biobank. Int. J. Epidemiol. 44, 1172–1180)).\\ | ||
| - | General practitioners invited all their patients between 25 and 50 years old (on Terschelling 18+), resulting in ~81.500 participants at [[1A|baseline]].\\ | + | General practitioners (GP's) invited all their patients between 25 and 50 years old (on Terschelling 18+), resulting in ~81.500 participants at [[1A|baseline]].\\ |
| These individuals were then asked to invite their family members (parents, partner, children, parents-in-law), resulting in an additional ~64.500 participants at [[1A|baseline]].\\ | These individuals were then asked to invite their family members (parents, partner, children, parents-in-law), resulting in an additional ~64.500 participants at [[1A|baseline]].\\ | ||
| ~21.500 interested individuals registered directly for [[1A|baseline]] participation via the Lifelines website. | ~21.500 interested individuals registered directly for [[1A|baseline]] participation via the Lifelines website. | ||
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| Most questionnaires and measurements are performed in both sexes.\\ | Most questionnaires and measurements are performed in both sexes.\\ | ||
| Notable exceptions: | Notable exceptions: | ||
| - | * [[ROAQ]], an [[additional assessments|additional assessment]] aimed at women | + | * [[ROAQ]], an [[additional assessments|additional assessment]] on reproductive health in women |
| - | * [[VESP]], an [[additional assessments|additional assessment]] aimed at men | + | * [[VESP]], an [[additional assessments|additional assessment]] on semen quality in men |
| * [[NEXT]], our birth cohort with an emphasis on pregnant women (but fathers are also included) | * [[NEXT]], our birth cohort with an emphasis on pregnant women (but fathers are also included) | ||
| - | Thus far, the gender of participants was assessed via self-report and via [[https://www.government.nl/topics/personal-data/personal-records-database-brp|BRP]] linkage (both **binary**).\\ | + | Thus far, the *binary* gender of participants was assessed via self-report and via [[https://www.government.nl/topics/personal-data/personal-records-database-brp|BRP]] linkage.\\ |
| - | More recently, attention is given to [[https://en.wikipedia.org/wiki/Gender_identity|gender identity]] and [[https://en.wikipedia.org/wiki/Non-binary_gender|non-binary genders]] within the cohort. | + | More recently, attention is given to *non-binary* [[sex & gender|gender]] within the cohort. |
| ===== Nationality and Ethnicity ===== | ===== Nationality and Ethnicity ===== | ||
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| ===== Mortality ===== | ===== Mortality ===== | ||
| - | As of July 2019, ~2000 participants have died. Although Lifelines continuously receives updates about the death of participants via the [[https://www.government.nl/topics/personal-data/personal-records-database-brp|BRP]], we do not know the [[https://en.wikipedia.org/wiki/Cause_of_death|cause of their death]]. Researchers interested in the causes of death may obtain this information via data linkage with [[http://www.cbs.nl/microdata|Statistics Netherlands]]. | + | Click [[mortality|here]] to learn more about the Lifelines death rate and causes of death. |
| ===== Family connections ===== | ===== Family connections ===== | ||
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| | Number of families | ^ Child(ren) = LL Participant(s) ||||| | | Number of families | ^ Child(ren) = LL Participant(s) ||||| | ||
| ^ Parent = LL participant | Total | 1 | 2 | 3 | 4 | 5 | | ^ Parent = LL participant | Total | 1 | 2 | 3 | 4 | 5 | | ||
| - | | Mother | ~2200 | ~1500 | ~600 | ~80 | <10 | <10 | | + | | Only the mother | ~2200 | ~1500 | ~600 | ~80 | <10 | <10 | |
| - | | Father | ~350 | ~250 | ~80 | ~10 | <10 | <10 | | + | | Only the father | ~350 | ~250 | ~80 | ~10 | <10 | <10 | |
| | Mother and father | ~5000 | ~2600 | ~2000 | ~350 | ~40 | <10 | | | Mother and father | ~5000 | ~2600 | ~2000 | ~350 | ~40 | <10 | | ||
| + | |||
| + | Other family connections (e.g. grandparent-grandchild, siblings) are present in the cohort as well. | ||
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| * Individual data from **governmental registries** (i.e. causes of death, socio-economic data) can be linked to Lifelines health-related data via [[http://www.cbs.nl/microdata|Statistics Netherlands]] | * Individual data from **governmental registries** (i.e. causes of death, socio-economic data) can be linked to Lifelines health-related data via [[http://www.cbs.nl/microdata|Statistics Netherlands]] | ||
| * Individual results from **pathological tests** (i.e. biopsies) can be linked to Lifelines health-related data (including self-reported [[cancer]]) via [[https://www.palga.nl|PALGA]] and [[https://www.zorgttp.nl|ZorgTTP]] | * Individual results from **pathological tests** (i.e. biopsies) can be linked to Lifelines health-related data (including self-reported [[cancer]]) via [[https://www.palga.nl|PALGA]] and [[https://www.zorgttp.nl|ZorgTTP]] | ||
| - | * Individual longitudinal **prescription medication** data from Dutch pharmacies can be linked to Lifelines health-related data (including self-reported [[medication]]) via [[http://www.iadb.nl|IADB]] | + | * Individual longitudinal **prescription medication** data from Dutch pharmacies can be linked to Lifelines health-related data (including self-reported [[medication]]) via [[http://www.iadb.nl|IADB]] (the {{ ::pharmlines_procedures_20210415.pdf|Pharmlines}} initiative) |
cohort.1591341741.txt.gz · Last modified: 2020/06/05 09:22 by trynke
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