urine_analyses
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| ====== Urine Sample Analyses ====== | ====== Urine Sample Analyses ====== | ||
| - | The following variables were assessed in fresh [[urine samples]] collected from [[start|Lifelines]] participants during [[1A Visit 2]] and [[2A Visit 2]] ([[sections|section]]: [[physical state]]).\\ | + | The following variables were assessed in fresh [[urine samples]] collected from [[start|Lifelines]] participants during [[1A Visit 2]], [[2A Visit 2]] and [[3A Visit 2]] ([[sections|section]]: [[physical state]]).\\ |
| Assessments were performed at the laboratory center of the [[https://www.umcg.nl|University Medical Center Groningen]] that is [[https://www.umcg.nl/NL/UMCG/Afdelingen/Laboratoriumgeneeskunde/Professionals/KwaliteitscertificatenAanvragen/Paginas/default.aspx|certified]] according to NEN-EN-ISO 9001:2008 and NEN-EN-ISO 15189:2012 standards.\\ | Assessments were performed at the laboratory center of the [[https://www.umcg.nl|University Medical Center Groningen]] that is [[https://www.umcg.nl/NL/UMCG/Afdelingen/Laboratoriumgeneeskunde/Professionals/KwaliteitscertificatenAanvragen/Paginas/default.aspx|certified]] according to NEN-EN-ISO 9001:2008 and NEN-EN-ISO 15189:2012 standards.\\ | ||
| For more information about individual assays, see [[https://www.umcg.nl/NL/UMCG/Afdelingen/Laboratoriumgeneeskunde/Professionals/bepalingenwijzer/Paginas/bepalingenwijzer.aspx|here]].\\ | For more information about individual assays, see [[https://www.umcg.nl/NL/UMCG/Afdelingen/Laboratoriumgeneeskunde/Professionals/bepalingenwijzer/Paginas/bepalingenwijzer.aspx|here]].\\ | ||
| - | Note that additional analyses were performed on [[blood samples]] collected on the same day. | + | Note that additional analyses were performed on [[blood analyses|blood]] samples collected on the same day. |
| ===== Assessments ===== | ===== Assessments ===== | ||
| - | **Creatinine** in the urine together with urine flow rate and creatinine levels in the blood can be used to calculate the creatinine clearance rate; the measurement is performed using a Roche Enzymatic assay with a detection limit of 1.1 – 516 mg/dL (predilution factor 20), traceable to reference isotope dilution mass spectroscopy.\\ | + | **Creatinine** in the urine together with urine flow rate and creatinine levels in the blood can be used to calculate the creatinine clearance rate; the measurement is performed using a Roche Enzymatic assay with a detection limit of 0,097 - 45 mmol/L (predilution factor 20), traceable to reference isotope dilution mass spectroscopy.\\ |
| **Albumin** was determined using Tinaquant turbidimetric assay (Roche) to determine Proteinuria – a marker suggestive of illness e.g. kidney injury. | **Albumin** was determined using Tinaquant turbidimetric assay (Roche) to determine Proteinuria – a marker suggestive of illness e.g. kidney injury. | ||
| - | | **English** | **Code** | **Variable** | N @ [[1A Visit 2|1A]] | N @ [[2A Visit 2|2A]] | **Age** | | + | | **English** | **Code** | **Variable** | **N @ [[1A Visit 2|1A]]** | **N @ [[2A Visit 2|2A]]** | **N @ [[3A Visit 2|3A]]** | **N @ 4A** | **Age** | |
| - | | was the 24h urine sample obtained within 24h (before or after) the blood sample? | ur24h_blood_all_m_1 | 24H_BL | | | 18+ | | + | | the 24h urine sample was obtained within 24h (before or after) the blood sample | ur24h_blood_all_m_1 | 24H_BL | ~131k | ~99k | ~78k | 100+ | 18+ | |
| - | | Are any urinations for the 24h urine sample missed? | ur24h_missed_all_m_1 | PLGEM | | | 18+ | | + | | the 24h urine sample was obtained within 24h (before or after) the early morning spot urine sample | ur24h_uems_all_m_1 | 24H_EMS | ~42k | - | - | - | 18+ | |
| - | | was the 24h urine sample obtained within 24h (before or after) the early morning spot urine sample? | ur24h_uems_all_m_1 | 24H_EMS | | | 18+ | | + | | Volume of 24h urine sample in milliliters | ur24h_volume_all_m_1 | U24HVOL | ~148k | ~103k | ~79k | 100+ | 18+ | |
| - | | Volume of 24h urine sample in milliliters | ur24h_volume_all_m_1 | U24HVOL | | | 18+ | | + | | Are any urinations for the 24h urine sample missed? | ur24h_missed_all_m_1 | PLGEM | ~148k | ~103k | ~79k | 100+ | 18+ | |
| - | | Albumin in 24h urine (mg/L) | ur24halbumin_result_all_m_1 | BABU24 | | | 18+ | | + | | Creatinine in 24-hrs urine (mmol/L) | ur24hcreatinine_result_all_m_1 | UKR24 | ~148k | ~103k | ~79k | 100+ | 18+ | |
| - | | Albumin in 24h urine (mg/L) | ur24halbumin_result_all_m_2 | PABU24 | | | 18+ | | + | | Albumin in 24h urine (mg/L) | ur24halbumin_result_all_m_1 | BABU24 | ~59k | ~0,2k | - | 100+ | 18+ | |
| - | | Creatinine in 24-hrs urine (mmol/L) | ur24hcreatinine_result_all_m_1 | UKR24 | | | 18+ | | + | | Albumin in 24h urine (mg/L) | ur24halbumin_result_all_m_2 | PABU24 | - | ~1,6k | - | - | 18+ | |
| - | | Magnesium in 24h urine (mg/L) | ur24hmagnesium_result_all_m_1 | MG24 | | | 18+ | | + | | Magnesium in 24h urine (mg/L) | ur24hmagnesium_result_all_m_1 | MG24 | - | ~2,3k | - | - | 18+ | |
| - | | was the early morning spot urine sample obtained within 24h (before or after) the blood sample? | urems_blood_all_m_1 | EMS_BL | | | 18+ | | + | | the early morning spot urine sample obtained within 24h (before or after) the blood sample | urems_blood_all_m_1 | EMS_BL | ~42k | - | - | - | 18+ | |
| - | | was the early morning spot urine sample obtained within 24h (before or after) the 24h urine sample? | urems_u24h_all_m_1 | EMS_24H | | | 18+ | | + | | was the early morning spot urine sample obtained within 24h (before or after) the 24h urine sample? | urems_u24h_all_m_1 | EMS_24H | ~42k| - | - | - | 18+ | |
| - | | Albumin in early morning spot urine (mg/L) | uremsalbumin_result_all_m_1 | BABUEMS | | | 18+ | | + | | Creatinine in early morning spot urine (mmol/L) | uremscreatinine_result_all_m_1 | UKREMS | ~55k | - | - | - | 18+ | |
| - | | Creatinine in early morning spot urine (mmol/L) | uremscreatinine_result_all_m_1 | UKREMS | | | 18+ | | + | | Albumin in early morning spot urine (mg/L) | uremsalbumin_result_all_m_1 | BABUEMS | ~55k | - | - | - | 18+ | |
| - | | was the to urine sample obtained within 24h (before or after) the blood sample? | urto_blood_all_m_1 | TO_BL | | | 8-17 | | + | | the to urine sample obtained within 24h (before or after) the blood sample | urto_blood_all_m_1 | TO_BL | ~7.5k | ~5.2k | ~1.6k | - | 8 – 17 | |
| - | | Are any urinations for the 24h urine sample missed? | urto_missed_all_m_1 | TOPLGEM | | | 8-17 | | + | | Are any urinations for the timed-overnight urine sample missed? | urto_missed_all_m_1 | TOPLGEM | ~8.6k | ~6.2k | ~1.8k | - | 8 – 17 | |
| - | | Volume of timed-overnight urine sample in milliliters | urto_volume_all_m_1 | TOVOL | | | 8-17 | | + | | Volume of timed-overnight urine sample in milliliters | urto_volume_all_m_1 | TOVOL | ~8.6k | ~6.2k | ~1.8k | - | 8 – 17 | |
| - | | Albumin in timed-overnight urine (mg/L) | urtoalbumin_result_all_m_1 | BABUTO | | | 8-17 | | + | | Creatinine in timed-overnight urine (mmol/L) | urtocreatinine_result_all_m_1 | UKRTO | ~8.6k | ~6.2k | ~1.8k | - | 8 – 17 | |
| - | | Creatinine in timed-overnight urine (mmol/L) | urtocreatinine_result_all_m_1 | UKRTO | | | 8-17 | | + | | Albumin in timed-overnight urine (mg/L) | urtoalbumin_result_all_m_1 | BABUTO | ~0,8k | - | - | - | 8 – 17 | |
| + | | Sodium in 24h urine (mg/L) | | NAUR24 | - | - | - | 100+ | 18+ | | ||
| + | | Potassium in 24h urine (mg/L) | | KAUR24 | - | - | - | 100+ | 18+ | | ||
| + | | Chloride in 24h urine (mg/L) | | CLUR24 | - | - | - | 100+ | 18+ | | ||
| + | \\ | ||
| + | ===Additional assessment SALT=== | ||
| + | In the context of the additional assessment on [[SALT|salt intake]], the following urine analyses have been performed. | ||
| + | | **Label English** | **Label Dutch** | **Code** | **Variable** | **Assessment** | **Age** | | ||
| + | | chloride in 24h urine (mmol/l) | chloride in 24-uurs urine (mmol/l) | ur24hchloride_result_all_m_1 | cl24 | [[SALT]] | 18+ | | ||
| + | | potassium in 24h urine (mmol/l) | kalium in 24-uurs urine (mmol/l) | ur24hpotassium_result_all_m_1 | k24 | [[SALT]] | 18+ | | ||
| + | | sodium in 24h urine (mmol/l) | natrium in 24-uurs urine (mmol/l) | ur24hsodium_result_all_m_1 | na24 | [[SALT]] | 18+ | | ||
urine_analyses.1602241753.txt.gz · Last modified: 2025/02/05 14:49 (external edit)
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