adii
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adii [2025/03/21 13:28] laura [Adapted Dietary Inflammatory Index (ADII)] |
adii [2025/03/25 16:11] (current) laura [Adapted Dietary Inflammatory Index (ADII)] |
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| Researchers from [[https://www.wur.nl/en/research-results/chair-groups/agrotechnology-and-food-sciences/human-nutrition-and-health.htm|Wageningen University and Research]] developed an adapted dietary inflammatory index (ADII) for approximately 69k adult participants in the Lifelines cohort who had a complete [[ffq|Food Frequency Questionnaire (FFQ)]]. ([[sections]]: [[Nutrition]] and [[secondary & linked variables]]).\\ | Researchers from [[https://www.wur.nl/en/research-results/chair-groups/agrotechnology-and-food-sciences/human-nutrition-and-health.htm|Wageningen University and Research]] developed an adapted dietary inflammatory index (ADII) for approximately 69k adult participants in the Lifelines cohort who had a complete [[ffq|Food Frequency Questionnaire (FFQ)]]. ([[sections]]: [[Nutrition]] and [[secondary & linked variables]]).\\ | ||
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| - | The Adapted Dietary Inflammatory Index can be requested in the [[https://data-catalogue.lifelines.nl/|Lifelines catalogue]].\\ | + | The Adapted Dietary Inflammatory Index can be requested in the [[https://data-catalogue.lifelines.nl/|Lifelines catalogue]]. When this data has been used in your research, the developing researchers recommend to include a reference to the the following paper: |
| - | \\ | + | * [[https://doi.org/10.3945/ajcn.112.056333|van Woudenbergh, G. J., Theofylaktopoulou, D., Kuijsten, A., Ferreira, I., van Greevenbroek, M. M., van der Kallen, C. J., ... & Feskens, E. J. (2013). Adapted dietary inflammatory index and its association with a summary score for low-grade inflammation and markers of glucose metabolism: the Cohort study on Diabetes and Atherosclerosis Maastricht (CODAM) and the Hoorn study. The American journal of clinical nutrition, 98(6), 1533-1542.]] |
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| ===== Background ===== | ===== Background ===== | ||
| - | [[https://doi.org/10.3945/ajcn.112.056333|Woudenbergh et al.]]: The Adapted Dietary Inflammatory Index (ADII) is a modified version of the original Dietary Inflammatory Index (DII), developed to quantify the inflammatory potential of an individual's diet based on available dietary data. The DII was created through an extensive literature review linking dietary components to inflammatory markers such as CRP, IL-6, and TNF-α. The ADII follows the same underlying methodology but is tailored to the specific nutrients and food items available within a given dataset, allowing for flexibility in its application across diverse dietary assessment tools. As a result, the ADII may exclude certain components present in the full DII, such as specific spices, flavonoids, or food additives, depending on data availability. Although this limits the scope of the index, previous research has shown that adapted versions of the DII can still effectively capture the inflammatory potential of diet and are particularly useful in large-scale epidemiological studies where complete dietary data may not be accessible. | + | As described by [[https://doi.org/10.3945/ajcn.112.056333|Woudenbergh et al.]], the Adapted Dietary Inflammatory Index (ADII) is a modified version of the original Dietary Inflammatory Index (DII), designed to assess the inflammatory potential of an individual's diet based on available dietary data. The original DII was developed through an extensive literature review linking various dietary components to inflammatory markers such as CRP, IL-6, and TNF-α. \\ |
| + | The ADII uses the same underlying methodology but excluded several nutrients and food items to avoid an overestimation of inflammatory effects of ethanol, fat, and energy. While this adaptation narrows the index's scope, previous research has shown that reduced versions of the DII can still effectively capture the inflammatory potential of diet and are particularly useful in large-scale epidemiological studies where complete dietary data may not be accessible. | ||
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| ===== Calculation of ADII ===== | ===== Calculation of ADII ===== | ||
| - | The ADII has been calculated based on the methodology as described in the paper from [[https://doi.org/10.3945/ajcn.112.056333|van Woudenbergh et al.]] (see background section). However, due to the limited availability of certain nutrients in the Lifelines [[ffq|Food Frequency Questionnaire (FFQ)]], the ADII was adapted even further to include only those nutrients and food items that were available. Specifically, this version of the ADII comprises 22 components, as depicted in the variable overview.\\ | + | The ADII was calculated following the methodology as described in [[https://doi.org/10.3945/ajcn.112.056333|van Woudenbergh et al.]] (see background section). However, due to the limited availability of certain nutrients in the Lifelines [[ffq|Food Frequency Questionnaire (FFQ)]], the ADII was further adapted to include only those nutrients and food items present in the Lifelines data. This version of the ADII includes 22 components, as depicted in the variable overview below.\\ |
| Please note: Caffeine is not a standard nutrient in the Dutch Food Composition Database (NEVO) and is therefore not directly included in the Lifelines FFQ. To account for this, caffeine intake was estimated based on average concentrations: 68 mg per 100 grams of coffee, 20 mg per 100 grams of tea, and 32 mg per 100 grams of energy drinks. | Please note: Caffeine is not a standard nutrient in the Dutch Food Composition Database (NEVO) and is therefore not directly included in the Lifelines FFQ. To account for this, caffeine intake was estimated based on average concentrations: 68 mg per 100 grams of coffee, 20 mg per 100 grams of tea, and 32 mg per 100 grams of energy drinks. | ||
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| === Use of the ADII === | === Use of the ADII === | ||
| - | As the ADII scores vary depending on the included population, together with the researchers it has been decided to distrubte ADII variables that depict the total intake per day for a specific ADII component. With this data, researchers can access a script, written bij the WUR researchers, to calculate your own ADII scores depending on: | + | Because the ADII scores may vary depending on the study population, it was decided to distribute ADII as variables representing daily intake per ADII component. This approach allows researchers to calculate customized ADII scores using the provided script. You are able to tailor your results to: |
| - | - //your specific population:// the results differ depending on the included participants. The syntax allows you to select your own population and alter the ADII scores given this population. | + | - //your specific population:// ADII results differ depending on the selected participants. The scripts enables users to define their own subpopulation and recalculate ADII scores accordingly. |
| - | - //your preference regarding the reliability inclusion:// with the ADII variables, the reliability variable is released as well. This reliability variable stems from the [[FFQ sum scores]] and gives the reliabilty of the results (reliable, unreliable, very unreliable). | + | - //your preference regarding the data reliability:// alongside the ADII variables, a reliability variable is provided. This reliability variable, based on the [[FFQ sum scores]], classifies the data as reliable, unreliable, or very unreliable, supporting better-informed analyses. |
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| ===== Variables ===== | ===== Variables ===== | ||
| - | | **Label English** | **Label Dutch** | **Code** | **Variable** | **Assessment** | **Age** | | + | | **Label English** | **Label Dutch** | **Code** | **Variable** | **Assessment** | **Age** | |
| - | | total energy intake per day expressed in kcal (for adii calculation) | totale energieinname per dag, uitgedrukt in kcal (voor berekening adii) | adii_kcal_adu_c_1 | kcal | sec* | 18+ | | + | | total energy intake per day expressed in kcal (for adii calculation) | totale energieinname per dag, uitgedrukt in kcal (voor berekening adii) | adii_kcal_adu_c_1 | kcal | sec* | 18+ | |
| - | | total protein intake in g/day (for adii calculation) | totale inname van eiwitten in g/dag (voor berekening adii) | adii_protein_adu_c_1 | eiwittot | sec* | 18+ | | + | | total protein intake in g/day (for adii calculation) | totale inname van eiwitten in g/dag (voor berekening adii) | adii_protein_adu_c_1 | eiwittot | sec* | 18+ | |
| - | | total saturated fatty acid intake in g/day (for adii calculation) | totale inname verzadigde vetzuren in g/dag (voor berekening adii) | adii_sfa_adu_c_1 | vetverz | sec* | 18+ | | + | | total saturated fatty acid intake in g/day (for adii calculation) | totale inname verzadigde vetzuren in g/dag (voor berekening adii) | adii_sfa_adu_c_1 | vetverz | sec* | 18+ | |
| - | | total monounsaturated fatty acid intake in g/day (for adii calculation) | totale inname van enkelvoudig onverzadigde vetzuren in g/dag (voor berekening adii) | adii_mufa_adu_c_1 | eovz | sec* | 18+ | | + | | total monounsaturated fatty acid intake in g/day (for adii calculation) | totale inname van enkelvoudig onverzadigde vetzuren in g/dag (voor berekening adii) | adii_mufa_adu_c_1 | eovz | sec* | 18+ | |
| - | | total trans fatty acid intake in g/day (for adii calculation) | totale inname van transvetzuren in g/dag (voor berekening adii) | adii_fattyacid_adu_c_1 | transvetz | sec* | 18+ | | + | | total trans fatty acid intake in g/day (for adii calculation) | totale inname van transvetzuren in g/dag (voor berekening adii) | adii_transfattyacid_adu_c_1 | transvetz | sec* | 18+ | |
| - | | total cholesterol intake in mg/day (for adii calculation) | totale cholesterolinname in mg/dag (voor berekening adii) | adii_cholesterol_adu_c_1 | cholesterol | sec* | 18+ | | + | | total cholesterol intake in mg/day (for adii calculation) | totale cholesterolinname in mg/dag (voor berekening adii) | adii_cholesterol_adu_c_1 | cholesterol | sec* | 18+ | |
| - | | total carbohydrate intake in g/day (for adii calculation) | totale inname van koolhydraten in g/dag (voor berekening adii) | adii_carbohydrate_adu_c_1 | khtot | sec* | 18+ | | + | | total carbohydrate intake in g/day (for adii calculation) | totale inname van koolhydraten in g/dag (voor berekening adii) | adii_carbohydrate_adu_c_1 | khtot | sec* | 18+ | |
| - | | total dietary fiber intake in g/day (for adii calculation) | totale inname van voedingsvezel in g/dag (voor berekening adii) | adii_fiber_adu_c_1 | vezel | sec* | 18+ | | + | | total dietary fiber intake in g/day (for adii calculation) | totale inname van voedingsvezel in g/dag (voor berekening adii) | adii_fiber_adu_c_1 | vezel | sec* | 18+ | |
| - | | total alcohol intake in g/day (for adii calculation) | totale inname van alcohol in g/dag (voor berekening adii) | adii_alcohol_adu_c_1 | alcohol | sec* | 18+ | | + | | total alcohol intake in g/day (for adii calculation) | totale inname van alcohol in g/dag (voor berekening adii) | adii_alcohol_adu_c_1 | alcohol | sec* | 18+ | |
| - | | total caffeine intake in g/day (for adii calculation) | totale cafeine inname in g/dag (voor berekening adii) | adii_caffeine_adu_c_1 | caffeine | sec* | 18+ | | + | | total caffeine intake in g/day (for adii calculation) | totale cafeine inname in g/dag (voor berekening adii) | adii_caffeine_adu_c_1 | caffeine | sec* | 18+ | |
| - | | total retinol activity equivalent/beta-carotene intake in mcg/day (for adii calculation) | totale inname van retinol activiteit equivalent/betacaroteen in mcg/dag (voor berekening adii) | adii_rae_adu_c_1 | RAE | sec* | 18+ | | + | | total retinol activity equivalent/beta-carotene intake in mcg/day (for adii calculation) | totale inname van retinol activiteit equivalent/betacaroteen in mcg/dag (voor berekening adii) | adii_rae_adu_c_1 | RAE | sec* | 18+ | |
| - | | total vitamin b1/thiamin intake in mg/day (for adii calculation) | totale inname van vitamine b1/thiamine in mg/day (voor berekening adii) | adii_vitaminb1_adu_c_1 | vitB1 | sec* | 18+ | | + | | total vitamin b1/thiamin intake in mg/day (for adii calculation) | totale inname van vitamine b1/thiamine in mg/day (voor berekening adii) | adii_vitaminb1_adu_c_1 | vitB1 | sec* | 18+ | |
| - | | total vitamin b2/riboflavin intake in mg/day (for adii calculation) | totale inname van vitamine b2/riboflavine in mg/dag (voor berekening adii) | adii_vitaminb2_adu_c_1 | vitB2 | sec* | 18+ | | + | | total vitamin b2/riboflavin intake in mg/day (for adii calculation) | totale inname van vitamine b2/riboflavine in mg/dag (voor berekening adii) | adii_vitaminb2_adu_c_1 | vitB2 | sec* | 18+ | |
| - | | total nicotinic acid/niacin/vitamin b3 intake in mg/day (for adii calculation) | totale inname van nicotinezuur/niacine/vitamin b3 in mg/dag (voor berekening adii) | adii_nicotinicacid_adu_c_1 | nicotinez | sec* | 18+ | | + | | total nicotinic acid/niacin/vitamin b3 intake in mg/day (for adii calculation) | totale inname van nicotinezuur/niacine/vitamin b3 in mg/dag (voor berekening adii) | adii_nicotinicacid_adu_c_1 | nicotinez | sec* | 18+ | |
| - | | total vitamin b6 intake in mg/day (for adii calculation) | totale inname van vitamin b6 in mg/dag (voor berekening adii) | adii_vitaminb6_adu_c_1 | vitB6 | sec* | 18+ | | + | | total vitamin b6 intake in mg/day (for adii calculation) | totale inname van vitamin b6 in mg/dag (voor berekening adii) | adii_vitaminb6_adu_c_1 | vitB6 | sec* | 18+ | |
| - | | total folate (natural folic acid) intake in mcg/day (for adii calculation) | totale inname van folaat (van nature aanwezig foliumzuur) in mcg/dag (voor berekening adii) | adii_folate_adu_c_1 | folaat | sec* | 18+ | | + | | total folate (natural folic acid) intake in mcg/day (for adii calculation) | totale inname van folaat (van nature aanwezig foliumzuur) in mcg/dag (voor berekening adii) | adii_folate_adu_c_1 | folaat | sec* | 18+ | |
| - | | total vitamin b12 intake in mcg/day (for adii calculation) | totale inname van vitamine b12 in mcg/dag (voor berekening adii) | adii_vitaminb12_adu_c_1 | vitB12 | sec* | 18+ | | + | | total vitamin b12 intake in mcg/day (for adii calculation) | totale inname van vitamine b12 in mcg/dag (voor berekening adii) | adii_vitaminb12_adu_c_1 | vitB12 | sec* | 18+ | |
| - | | total vitamin c intake in mg/day (for adii calculation) | totale inname van vitamine c in mg/dag (voor berekening adii) | adii_vitaminc_adu_c_1 | vitC | sec* | 18+ | | + | | total vitamin c intake in mg/day (for adii calculation) | totale inname van vitamine c in mg/dag (voor berekening adii) | adii_vitaminc_adu_c_1 | vitC | sec* | 18+ | |
| - | | total vitamin d intake in mcg/day (for adii calculation) | totale inname van vitamine d in mcg/dag (voor berekening adii) | adii_vitamind_adu_c_1 | vitD | sec* | 18+ | | + | | total vitamin d intake in mcg/day (for adii calculation) | totale inname van vitamine d in mcg/dag (voor berekening adii) | adii_vitamind_adu_c_1 | vitD | sec* | 18+ | |
| - | | total vitamin e intake in mg/day (for adii calculation) | totale inname van vitamine e in mg/dag (voor berekening adii) | adii_vitamine_adu_c_1 | vitE | sec* | 18+ | | + | | total vitamin e intake in mg/day (for adii calculation) | totale inname van vitamine e in mg/dag (voor berekening adii) | adii_vitamine_adu_c_1 | vitE | sec* | 18+ | |
| - | | total iron intake in mg/day (for adii calculation) | totale ijzerinname in mg/dag (voor berekening adii) | adii_iron_adu_c_1 | ijzertot | sec* | 18+ | | + | | total iron intake in mg/day (for adii calculation) | totale ijzerinname in mg/dag (voor berekening adii) | adii_iron_adu_c_1 | ijzertot | sec* | 18+ | |
| - | | total zinc intake in mg/day (for adii calculation) | totale zinkinname in mg/dag (voor berekening adii) | adii_zinc_adu_c_1 | zink | sec* | 18+ | | + | | total zinc intake in mg/day (for adii calculation) | totale zinkinname in mg/dag (voor berekening adii) | adii_zinc_adu_c_1 | zink | sec* | 18+ | |
| - | | total tea intake in g/day (for adii calculation) | totale inname van thee (voor berekening adii) | adii_tea_adu_c_1 | thee | sec* | 18+ | | + | | total tea intake in g/day (for adii calculation) | totale inname van thee (voor berekening adii) | adii_tea_adu_c_1 | thee | sec* | 18+ | |
| - | | reliability of results (for adii calculation) | betrouwbaarheid van de waarden (voor berekening adii) | adii_reliability_adu_c_1 | Betrouwbaarheid | sec* | 18+ | | + | | reliability of results (for adii calculation) | betrouwbaarheid van de waarden (voor berekening adii) | adii_reliability_adu_c_1 | Betrouwbaarheid | sec* | 18+ | |
| * All ADII variables are included as assessment 'sec' as the data originates from several assessments. | * All ADII variables are included as assessment 'sec' as the data originates from several assessments. | ||
adii.1742560113.txt.gz · Last modified: 2025/03/21 13:28 by laura
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