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spirometry_validation [2021/05/06 17:25]
laura
spirometry_validation [2022/08/01 15:30] (current)
laura [Validation]
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 ===== Validation ===== ===== Validation =====
-[[Pulmonary Function Test|Spirometry]] is performed according to Standard Operating Procedures using the WEllch ​Allyn SpiroPerfect device. Judgment on technical correctness is performed by a Lifelines assistant, a pulmonologist,​ or both, according to a standard review procedure. Only data from pulmonary function tests that are judged to be technically correct should be used in the analyses. Technically correct is defined as:+[[Pulmonary Function Test|Spirometry]] is performed according to Standard Operating Procedures using the Welch Allyn SpiroPerfect device. Judgment on technical correctness is performed by a Lifelines assistant, a pulmonologist,​ or both, according to a standard review procedure. Only data from pulmonary function tests that are judged to be technically correct should be used in the analyses. Technically correct is defined as:
   * Test performed according to ATS criteria or   * Test performed according to ATS criteria or
   * Test not performed according to ATS criteria, but clinically reliable.   * Test not performed according to ATS criteria, but clinically reliable.
 In case both the pulmonologist and the Lifelines assistant judged the technical correctness,​ the priority is given to the judgment of the pulmonologist.\\ In case both the pulmonologist and the Lifelines assistant judged the technical correctness,​ the priority is given to the judgment of the pulmonologist.\\
 **Important:​** part of the spirometry results have been listed as technically invalid, as a result the researchers from the UMCG recommend you to __NOT__ use these results in analyses.\\ **Important:​** part of the spirometry results have been listed as technically invalid, as a result the researchers from the UMCG recommend you to __NOT__ use these results in analyses.\\
-\\+
 === Validation rules === === Validation rules ===
 To select only technically valid measurements the following rules were applied: To select only technically valid measurements the following rules were applied:
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 |Other case|Spirometry is not technically correct| |Other case|Spirometry is not technically correct|
  
-\\ 
-\\ 
 ===== Reference values ===== ===== Reference values =====
 Reference values based on age, height, and sex are calculated based on the Global Lung Function Initiative (GLI) using the [[https://​www.ers-education.org/​guidelines/​global-lung-function-initiative.aspx|GLI provided syntax codes and databases]]. ​ Reference values based on age, height, and sex are calculated based on the Global Lung Function Initiative (GLI) using the [[https://​www.ers-education.org/​guidelines/​global-lung-function-initiative.aspx|GLI provided syntax codes and databases]]. ​
- 
  
 === Remarks UMCG researcher === === Remarks UMCG researcher ===
   * It is important to note that ethnicity has not been taken into account. Everyone has been treated as Caucasian.   * It is important to note that ethnicity has not been taken into account. Everyone has been treated as Caucasian.
-  * There are a few adults subjects with a huge difference in height between [[1a_visit_1|1A visit 1]] and [[2a_visit_1|2A visit 1]] resulting in a huge difference in reference values. It is recommended to exclude the adult subjects with a height difference of more than 5 cm using the height variable. +  * There are a few adults subjects with a huge difference in height between [[1a_visit_1|1A visit 1]] and [[2a_visit_1|2A visit 1]] resulting in a huge difference in reference values. It is recommended to exclude the adult subjects with a height difference of more than 5 cm using the height variable.\\
  
 +===== Article =====
 +  * Mahon, G. M., Koppelman, G. H., & Vonk, J. M. (2021). Grandmaternal smoking, asthma and lung function in the offspring: the Lifelines cohort study. Thorax, 76(5), 441-447. DOI: 10.1136/​thoraxjnl-2020-215232\\
  
 ===== Variables ===== ===== Variables =====
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 | FEF75 % predicted ​                                           | FEF75 % voorspeld ​                                                  | fef75_percpredicted_all_c_1 ​   | fef75pp ​                 | [[1A visit 1|1A]] [[2A visit 1|2A]] ​ | 18+      | | FEF75 % predicted ​                                           | FEF75 % voorspeld ​                                                  | fef75_percpredicted_all_c_1 ​   | fef75pp ​                 | [[1A visit 1|1A]] [[2A visit 1|2A]] ​ | 18+      |
 | FEF25_75 % predicted ​                                        | FEF25_75 % voorspeld ​                                               | fef2575_percpredicted_all_c_1 ​ | fef2575pp ​               | [[1A visit 1|1A]] [[2A visit 1|2A]] ​ | 18+      | | FEF25_75 % predicted ​                                        | FEF25_75 % voorspeld ​                                               | fef2575_percpredicted_all_c_1 ​ | fef2575pp ​               | [[1A visit 1|1A]] [[2A visit 1|2A]] ​ | 18+      |
-| change in FEV1 2A versus 1A (liter per year)                 | verandering in FEV1 2A versus 1A (liter per jaar)                   | fev1_change_all_c_1 ​           | dfev1                    | [[1A visit 1|1A]] ​[[2A visit 1|2A]] ​ | 18+      | +| change in FEV1 2A versus 1A (liter per year)                 | verandering in FEV1 2A versus 1A (liter per jaar)                   | fev1_change_all_c_1 ​           | dfev1                    | [[2A visit 1|2A]] ​                   | 18+      | 
-| change in FEV1FVC 2A versus 1A (liter per year)              | verandering in FEV1FVC 2A versus 1A (liter per jaar)                | fev1fvc_change_all_c_1 ​        | dfev1fvc ​                ​| ​[[1A visit 1|1A]] ​[[2A visit 1|2A]] ​ | 18+      | +| change in FEV1FVC 2A versus 1A (liter per year)              | verandering in FEV1FVC 2A versus 1A (liter per jaar)                | fev1fvc_change_all_c_1 ​        | dfev1fvc ​                | [[2A visit 1|2A]] ​                   | 18+      | 
-| change in FVC 2A versus 1A (liter per year)                  | verandering in FVC1 2A versus 1A (liter per jaar)                   | fvc_change_all_c_1 ​            | dfvc                     ​| ​[[1A visit 1|1A]] ​[[2A visit 1|2A]] ​ | 18+      | +| change in FVC 2A versus 1A (liter per year)                  | verandering in FVC1 2A versus 1A (liter per jaar)                   | fvc_change_all_c_1 ​            | dfvc                     | [[2A visit 1|2A]] ​                   | 18+      | 
-| change in FEF75 2A versus 1A (liter per second per year)     | verandering in FEF75 2A versus 1A  (liter per seconde per jaar)     | fef75_change_all_c_1 ​          | dfef75 ​                  ​| ​[[1A visit 1|1A]] ​[[2A visit 1|2A]] ​ | 18+      | +| change in FEF75 2A versus 1A (liter per second per year)     | verandering in FEF75 2A versus 1A  (liter per seconde per jaar)     | fef75_change_all_c_1 ​          | dfef75 ​                  | [[2A visit 1|2A]] ​                   | 18+      | 
-| change in FEF25_75 2A versus 1A (liter per second per year)  | verandering in FEF25_75 2A versus 1A  (liter per seconde per jaar)  | fef2575_change_all_c_1 ​        | dfef2575 ​                ​| ​[[1A visit 1|1A]] ​[[2A visit 1|2A]] ​ | 18+      | +| change in FEF25_75 2A versus 1A (liter per second per year)  | verandering in FEF25_75 2A versus 1A  (liter per seconde per jaar)  | fef2575_change_all_c_1 ​        | dfef2575 ​                | [[2A visit 1|2A]] ​                   | 18+      | 
-| difference in body length adults 2A versus 1A                | verschil in lichaamslengte volwassenen 2A versus 1A                 | spirometry_bodylength_all_c_1 ​ | heightdifference_adults ​ | [[1A visit 1|1A]] ​[[2A visit 1|2A]] ​ | 18+      |+| difference in body length adults 2A versus 1A                | verschil in lichaamslengte volwassenen 2A versus 1A                 | spirometry_bodylength_all_c_1 ​ | heightdifference_adults ​ | [[2A visit 1|2A]] ​                   | 18+      |
spirometry_validation.1620314722.txt.gz · Last modified: 2021/05/06 17:25 by laura