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        <title>family_relations</title>
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        <description>Family Relations

The Lifelines cohort consists of many family relationships. During the inclusion into Lifelines, participants were asked if they had any family members who would be interested in joining the cohort. As a result Lifelines is one of the largest 3 generation cohorts available.</description>
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        <title>skin_autofluorescence - [Table] </title>
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        <description>Skin Autofluorescence

Skin autofluorescence (SAF) (section: physical state) was measured in adult Lifelines participants during 1A Visit 1 (n = ~84.000, n = ~76,000 after rigorous quality control). 

Background

SAF was measured in Lifelines participants using the AGE Reader, a noninvasive instrument to determine the accumulation of</description>
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        <title>earq - [Table] </title>
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        <description>Earthquakes (EARQ)

Earthquakes is the name of an additional questionnaire that was implemented in Lifelines at the initiative of the Department of Social Psychology of the University of Groningen.

The aim of the questionnaire was to assess the health impact of earthquake-related damage experienced by inhabitants of Groningen due to the</description>
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        <description>Parental Bonding Instrument (PBI)

The Parental Bonding Instrument is a questionnaire that can be used to study optimal and distorted parental bonding. It assesses the bond between the participant and the two parental figures that or played the most important role in his/her upbringing (&#039;parent 1&#039; and &#039;parent 2&#039;).</description>
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        <title>treatment_general - [Table] </title>
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        <description>Treatment (general)

Lifelines participants were asked about the medical treatments they underwent in their lifetime, in addition to hospitalization, surgery, and medication (section: medical treatment).

In the context of the additional assessments DEPQ and DEAQ, the LIDAS  was sent to a subgroup of participants to collect information on depression and anxiety, among which treatment for mental disorders. Part of thse variables have been included in the</description>
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        <title>depression_lidas - [Table] </title>
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        <description>Depression &amp; Anxiety (LIDAS)

The Lifetime Depression Assessment Self-Report (LIDAS) digital questionnaire is largely based on the WHO&#039;s Composite International Diagnostic Interview short form (CIDI-sf) for depression, and is used to identify persons who have or have not been depressed in their lifetime.</description>
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        <title>mental_illnesses - [Table] </title>
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        <description>Mental Illnesses

Lifelines participants were asked whether they (ever) had a mental illness (section: Diseases &amp; symptoms and Mental health).

Note that questions on eating disorders are listed here, and that some mental illnesses are assessed in more detail (see list of subsections under Mental health). Psychosis was assessed using the</description>
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        <description>Memory and Cognition Test (MCOT)

MCOT is the name of an additional assessment in which a memory and cognition test is performed via a smartphone app, in a subgroup of adult Lifelines participants. Implementation of this additional study in Lifelines was initiated by the department of Nephrology of the University Medical Center Groningen. The purpose of this study was to determine reference values for the digital version of the test, since they may differ from the available reference values that…</description>
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        <title>cohort</title>
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        <description>General Cohort &amp; Factsheets

The general population cohort of Lifelines consists of 167.729 participants, identified with a Lifelines-ID.


Recruitment

Lifelines participants were initially recruited through general practitioners in the three provinces in the</description>
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        <description>NEO Personality Inventory

The NEO-PI-R is a self-report instrument that measures the five most important domains of personality: neuroticism, extraversion, openness, agreeableness and conscientiousness (section: mental health).

Lifelines implemented two abbreviated versions of the NEO at</description>
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        <description>Mini Mental State Examination (MMSE)

The Mini International Neuropsychiatric Interview (MINI) (section: mental health) was measured in all elderly Lifelines participants during:

	*  1A Visit 1 (65+, n = ~13.000) 
	*  3A Visit 1 (65+, n = ~15.000)
	*  4A Visit 1 (65+, currently ongoing)

Background

The Mini Mental State Examination (</description>
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