activelife
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Table of Contents
ActiveLIFE (ACLI)
ActiveLIFE is one of Lifelines' additional assessments were physical activity of the participants is monitored by an accelerometer. This assessment is a collaboration between Lifelines and the Radboud university medical center, department of Medical BioSciences. This research is funded by the Dutch Heart Foundation and Brain Foundation Netherlands, and the Dutch Ministry of Health, Welfare and Sport.
Aim
The goal of ActiveLIFE is to create a large Dutch dataset of thigh- and wrist-worn accelerometry. These data will allow to determine lifestyle behavior such as physical activity, sitting behavior, and sleep. These data will be combined with information about other lifestyle behaviors, health, and risk factors. Combining these data will contribute to the refining of current physical activity guidelines and accelerate lifestyle and prevention research. ActiveLIFE aims to collect ~60,000 accelerometry measurements in the 4th research round of Lifelines.
Protocol
ActiveLIFE is an additional measurement, part of the 4th research round measurements. Lifelines participants wear a triaxial thigh-worn accelerometer (Axivity AX3, settings: 100 Hz, 8g) for 8 consecutive days. A subsample of at least 10% will be asked to wear both a thigh- and wrist-worn accelerometer. Raw accelerometry data will be processed into physical activity metrics, including steps per day, time spent in moderate-to-vigorous physical activity, light-intensity physical activity, sedentary behaviour, and sleep. More information can be found on the ActiveLIFE website (www.radboudumc.nl/lopende-onderzoeken/activelife) and in the ActiveLIFE protocol paper of Netten et al1.
Inclusion criteria
Age: ≥8 years old
Participant is invited for the 4th assessment (4A).
Exclusion criteria
Allergy to one of the materials used for the accelerometry measurement.
Timeline data collection
July 2025 - December 2028.
Data processing
Thigh-worn accelerometer data: ActiPASS algorithm (Version 2025.04).
Wrist-worn accelerometer data: UK Biobank Accelerometer algorithm (Version 7.5.0).
Measurements performed
12,940 accelerometry measurements collected until July 2026.
Response rate: 85%.
Participant information movie
Publications
1. Netten et al. (under submission)
Variables
Data is under embargo, but available on request.
| Variable Most variables are available 7 times, one for every measurement day. | Description We provide a description of the variables for Day 1, but the same description applies to the other measurement days (1-7) | Assessment | Age |
| Year | Year day 1 | 4A | 8+ |
| Month | Month day 1 | 4A | 8+ |
| QC_Status | Auto detected preliminary quality check (QC) flag. | 4A | 8+ |
| Sensor_Errs | Sensor errors | 4A | 8+ |
| NumDays | Number of days present in the accelerometer data after automatically trimming Non-wear (NW) days in the beginning and end | 4A | 8+ |
| NumValidDays | Number of valid days (default valid day criteria is based on at least 20h of wear time) | 4A | 8+ |
| Day_1-7 | The day name in English. Measurement day 1-7 | 4A | 8+ |
| Weekend_1-7 | A T/F flag whether the given day is Saturday or Sunday. Measurement day 1-7 | 4A | 8+ |
| DayStart_1-7 | The start of the day in 24h format (HH:MM:SS). This is normally 00:00:00 for full days. Measurement day 1-7 | 4A | 8+ |
| DayStop_1-7 | The end of the day in 24h format (HH:MM:SS). This is normally 23:59:59 for full days. Measurement day 1-7 | 4A | 8+ |
| Day_QC_1-7 | The auto detected quality check flag for the day. possible values: “OK”, “Check” or “NotOK” . Measurement day 1-7 | 4A | 8+ |
| refPosInfo_1-7 | Automatic individual calibration angles (in degrees) for this day. Given as absolute inclination and forward backward inclination of thigh at the reference-position. Measurement day 1-7 | 4A | 8+ |
| NotEnoughWear_1-7 | A flag indicating if the day has not enough wear time (20 hrs). Measurement day 1-7 | 4A | 8+ |
| NoWlk_1-7 | A flag indicating if the day has less than 30s of walking. Measurement day 1-7 | 4A | 8+ |
| TooMuchOther_1-7 | A flag indicating if more than 30 minutes of “other” exist in the day . Measurement day 1-7 | 4A | 8+ |
| TooMuchStair_1-7 | A flag indicating more than 120 minutes of stair-walking present in the day. Measurement day 1-7 | 4A | 8+ |
| NoSleepInt_1-7 | A sleep-interval (a mid-point of a sleep interval to be precise) is not found within the day. Measurement day 1-7 | 4A | 8+ |
| NumPrimaryBDs_1-7 | Number of primary bedtimes (mid points) found within the current day. Measurement day 1-7 | 4A | 8+ |
| NumExtraBDs_1-7 | Number of possible extra bedtimes found within the current day. Measurement day 1-7 | 4A | 8+ |
| Duration_1-7 | Total measured time for the day (1440 minutes for full days). Measurement day 1-7 | 4A | 8+ |
| NonWear_1-7 | Time of auto or manually defined non-wear (NW) during the day. Measurement day 1-7 | 4A | 8+ |
| AwakeNW_1-7 | The time of NW outside any periods flagged as sleep-intervals. Measurement day 1-7 | 4A | 8+ |
| SlpIntNW_1-7 | The time of NW inside any periods flagged as sleep-intervals. Measurement day 1-7 | 4A | 8+ |
| ValidDuration_1-7 | The valid time which can be used for analysis for this day. Measurement day 1-7 | 4A | 8+ |
| Awake_1-7 | The time within ValidDuration of this calendar day which is not flagged as belonging to a sleep-interval. Measurement day 1-7 | 4A | 8+ |
| SleepInterval_1-7 | The time within ValidDuration of this calendar day which is flagged as belonging to a sleep-interval. Measurement day 1-7 | 4A | 8+ |
| Bedtime_1-7 | The time within this calendar day which is flagged as belonging to a times-in-bed. Measurement day 1-7 | 4A | 8+ |
| Sleep_1-7 | Total sleep time within ValidDuration of this calendar day. Measurement day 1-7 | 4A | 8+ |
| SleepInBed_1-7 | The total times of sleep within a bedtime. This is also the time of sleep inside sleep_intervals by definition of sleep-interval. Measurement day 1-7 | 4A | 8+ |
| Walk_Slow_1-7 | Time of walking with a cadence lower than 100. Measurement day 1-7 | 4A | 8+ |
| Walk_Fast_1-7 | Time of walking with a cadence equal or higher than 100. Measurement day 1-7 | 4A | 8+ |
| NumSteps_1-7 | Total number of steps per this day. Measurement day 1-7 | 4A | 8+ |
| NumStepsWalk_1-7 | Number of steps during walking. Measurement day 1-7 | 4A | 8+ |
| NumStepsRun_1-7 | Number of steps during running. Measurement day 1-7 | 4A | 8+ |
| TotalTransitions_1-7 | Number of activity transition. Measurement day 1-7 | 4A | 8+ |
| Lie_1-7 | Time of lying. Measurement day 1-7 | 4A | 8+ |
| Lie_T30min_1-7 | Total time duration of segments longer than 30 minutes of 'Lie' . Measurement day 1-7 | 4A | 8+ |
| Lie_N30min_1-7 | Number of segments longer than 30 minutes of 'Lie' . Measurement day 1-7 | 4A | 8+ |
| Lie_Tmax_1-7 | Time of longest continuous 'Lie' segment. Measurement day 1-7 | 4A | 8+ |
| Lie_NBreaks_1-7 | Number of breaks from lying postures. Measurement day 1-7 | 4A | 8+ |
| Sit_1-7 | Time of sitting. Measurement day 1-7 | 4A | 8+ |
| Sit_T30min_1-7 | Total time duration of segments longer than 30 minutes of 'Sit . Measurement day 1-7 | 4A | 8+ |
| Sit_N30min_1-7 | Number of segments longer than 30 minutes of 'Sit . Measurement day 1-7 | 4A | 8+ |
| Sit_Tmax_1-7 | Time of longest continuous 'Sit segment. Measurement day 1-7 | 4A | 8+ |
| Sit_NBreaks_1-7 | Number of breaks of sitting posture. Measurement day 1-7 | 4A | 8+ |
| SitLie_1-7 | Time of sitting or lying. Measurement day 1-7 | 4A | 8+ |
| SitLie_T30min_1-7 | Total time duration of segments longer than 30 minutes of 'SitLie' . Measurement day 1-7 | 4A | 8+ |
| SitLie_N30min_1-7 | Number of segments longer than 30 minutes of 'SitLie' . Measurement day 1-7 | 4A | 8+ |
| SitLie_Tmax_1-7 | Time of longest continuous 'SitLie' segment. Measurement day 1-7 | 4A | 8+ |
| SitLie_NBreaks_1-7 | Number of breaks of sitting or lying postures. Measurement day 1-7 | 4A | 8+ |
| Stand_1-7 | Time of standing. Measurement day 1-7 | 4A | 8+ |
| Stand_T30min_1-7 | Total time duration of segments longer than 30 minutes of 'Stand' . Measurement day 1-7 | 4A | 8+ |
| Stand_N30min_1-7 | Number of segments longer than 30 minutes of 'Stand' . Measurement day 1-7 | 4A | 8+ |
| Stand_Tmax_1-7 | Time of longest continuous 'Stand' segment. Measurement day 1-7 | 4A | 8+ |
| Stand_NBreaks_1-7 | Number of breaks from a standing posture. Measurement day 1-7 | 4A | 8+ |
| Move_1-7 | The time of 'move'. 'Move' is defined as periods where person is in standing posture with certain movements above the threshold for standing posture (ex. intermittent steps), but no purposeful walking. Measurement day 1-7 | 4A | 8+ |
| Move_T30min_1-7 | Total time duration of segments longer than 30 minutes of 'Move' . Measurement day 1-7 | 4A | 8+ |
| Move_N30min_1-7 | Number of segments longer than 30 minutes of 'Move' . Measurement day 1-7 | 4A | 8+ |
| Move_Tmax_1-7 | Time of longest continuous 'Move' segment. Measurement day 1-7 | 4A | 8+ |
| Move_NBreaks_1-7 | Number of breaks of moving postures. Measurement day 1-7 | 4A | 8+ |
| StandMove_1-7 | Time of standing or moving. Measurement day 1-7 | 4A | 8+ |
| StandMove_T30min_1-7 | Total time duration of segments longer than 30 minutes of 'StandMove' . Measurement day 1-7 | 4A | 8+ |
| StandMove_N30min_1-7 | Number of segments longer than 30 minutes of 'StandMove' . Measurement day 1-7 | 4A | 8+ |
| StandMove_Tmax_1-7 | Time of longest continuous 'StandMove' segment. Measurement day 1-7 | 4A | 8+ |
| StandMove_NBreaks_1-7 | Number of breaks of standing or moving postures. Measurement day 1-7 | 4A | 8+ |
| Walk_1-7 | Time of walking. Measurement day 1-7 | 4A | 8+ |
| Walk_T30min_1-7 | Total time duration of segments longer than 30 minutes of 'Walk' . Measurement day 1-7 | 4A | 8+ |
| Walk_N30min_1-7 | Number of segments longer than 30 minutes of 'Walk' . Measurement day 1-7 | 4A | 8+ |
| Walk_Tmax_1-7 | Time of longest continuous 'Walk' segment. Measurement day 1-7 | 4A | 8+ |
| Walk_NBreaks_1-7 | Number of breaks from walking. Measurement day 1-7 | 4A | 8+ |
| Run_1-7 | Time of running. Measurement day 1-7 | 4A | 8+ |
| Run_T30min_1-7 | Total time duration of segments longer than 30 minutes of 'Run' . Measurement day 1-7 | 4A | 8+ |
| Run_N30min_1-7 | Number of segments longer than 30 minutes of 'Run' . Measurement day 1-7 | 4A | 8+ |
| Run_Tmax_1-7 | Time of longest continuous 'Run' segment. Measurement day 1-7 | 4A | 8+ |
| Run_NBreaks_1-7 | Number of breaks from running. Measurement day 1-7 | 4A | 8+ |
| Stair_1-7 | Time of stair-walking (all stair walking like activities are counted. i.e. terrain walking etc.). Measurement day 1-7 | 4A | 8+ |
| Stair_T30min_1-7 | Total time duration of segments longer than 30 minutes of 'Stair' . Measurement day 1-7 | 4A | 8+ |
| Stair_N30min_1-7 | Number of segments longer than 30 minutes of 'Stair' . Measurement day 1-7 | 4A | 8+ |
| Stair_Tmax_1-7 | Time of longest continuous 'Stair' segment. Measurement day 1-7 | 4A | 8+ |
| Stair_NBreaks_1-7 | Number of breaks from stairclimbin. Measurement day 1-7 | 4A | 8+ |
| Cycle_1-7 | Time of cycling. Measurement day 1-7 | 4A | 8+ |
| Cycle_T30min_1-7 | Total time duration of segments longer than 30 minutes of 'Cycle' . Measurement day 1-7 | 4A | 8+ |
| Cycle_N30min_1-7 | Number of segments longer than 30 minutes of 'Cycle' . Measurement day 1-7 | 4A | 8+ |
| Cycle_Tmax_1-7 | Time of longest continuous 'Cycle' segment. Measurement day 1-7 | 4A | 8+ |
| Cycle_NBreaks_1-7 | Number of breaks of sitting or lying postures. (i.e. this is the number of times a person rises from cycling posture). Measurement day 1-7 | 4A | 8+ |
| Upright_1-7 | Time of all upright activities/postures (i.e. Stand + Move + Walk + Run + Stair). Measurement day 1-7 | 4A | 8+ |
| Upright_T30min_1-7 | Total time duration of segments longer than 30 minutes of 'Upright' . Measurement day 1-7 | 4A | 8+ |
| Upright_N30min_1-7 | Number of segments longer than 30 minutes of 'Upright' . Measurement day 1-7 | 4A | 8+ |
| Upright_Tmax_1-7 | Time of longest continuous 'Upright' segment. Measurement day 1-7 | 4A | 8+ |
| Upright_NBreaks_1-7 | Number of breaks from upright postures. Measurement day 1-7 | 4A | 8+ |
| Other_1-7 | Time of activities in “Other” postures/activities with movements which cannot be classified into known activities/postures. Measurement day 1-7 | 4A | 8+ |
| Other_T30min_1-7 | Total time duration of segments longer than 30 minutes of 'Other' . Measurement day 1-7 | 4A | 8+ |
| Other_N30min_1-7 | Number of segments longer than 30 minutes of 'Other' . Measurement day 1-7 | 4A | 8+ |
| Other_Tmax_1-7 | Time of longest continuous 'Other' segment. Measurement day 1-7 | 4A | 8+ |
| Other_NBreaks_1-7 | Number of breaks a 'Other' posture. Measurement day 1-7 | 4A | 8+ |
| INT1_1-7 | Time spent on activities classified as sedentary . Measurement day 1-7 | 4A | 8+ |
| INT1_T30min_1-7 | Total time duration of segments longer than 30 minutes of 'INT1' . Measurement day 1-7 | 4A | 8+ |
| INT1_N30min_1-7 | Number of segments longer than 30 minutes of 'INT1' . Measurement day 1-7 | 4A | 8+ |
| INT1_Tmax_1-7 | Time of longest continuous 'INT1' segment. Measurement day 1-7 | 4A | 8+ |
| INT1_NBreaks_1-7 | Number of breaks of sitting or lying postures. (i.e. this is the number of times a person rises from a sitting or a lying posture). Measurement day 1-7 | 4A | 8+ |
| INT2_1-7 | Time spent on activities classified as low physical activity. Measurement day 1-7 | 4A | 8+ |
| INT2_T30min_1-7 | Total time duration of segments longer than 30 minutes of 'INT2' . Measurement day 1-7 | 4A | 8+ |
| INT2_N30min_1-7 | Number of segments longer than 30 minutes of 'INT2' . Measurement day 1-7 | 4A | 8+ |
| INT2_Tmax_1-7 | Time of longest continuous 'INT2' segment. Measurement day 1-7 | 4A | 8+ |
| INT2_NBreaks_1-7 | Number of breaks of sitting or lying postures. (i.e. this is the number of times a person rises from a INT2 posture). Measurement day 1-7 | 4A | 8+ |
| INT2_Amb_1-7 | Time spent on ambulatory activities classified as low physical activity (standing excluded). Measurement day 1-7 | 4A | 8+ |
| INT2_Amb_T30min_1-7 | Total time duration of segments longer than 30 minutes of 'INT2_Amb' . Measurement day 1-7 | 4A | 8+ |
| INT2_Amb_N30min_1-7 | Number of segments longer than 30 minutes of 'INT2_Amb' . Measurement day 1-7 | 4A | 8+ |
| INT2_Amb_Tmax_1-7 | Time of longest continuous 'INT2_Amb' segment. Measurement day 1-7 | 4A | 8+ |
| INT2_Amb_NBreaks_1-7 | Number of breaks from a licht-intensity activity. Measurement day 1-7 | 4A | 8+ |
| INT3_1-7 | Time spent on activities classified as moderate physical activity. Measurement day 1-7 | 4A | 8+ |
| INT3_T30min_1-7 | Total time duration of segments longer than 30 minutes of 'INT3' . Measurement day 1-7 | 4A | 8+ |
| INT3_N30min_1-7 | Number of segments longer than 30 minutes of 'INT3' . Measurement day 1-7 | 4A | 8+ |
| INT3_Tmax_1-7 | Time of longest continuous 'INT3' segment. Measurement day 1-7 | 4A | 8+ |
| INT3_NBreaks_1-7 | Number of breaks from INT2. Measurement day 1-7 | 4A | 8+ |
| INT4_1-7 | Time spent on activities classified as vigorous physical activity. Measurement day 1-7 | 4A | 8+ |
| INT4_T30min_1-7 | Total time duration of segments longer than 30 minutes of 'INT4' . Measurement day 1-7 | 4A | 8+ |
| INT4_N30min_1-7 | Number of segments longer than 30 minutes of 'INT4' . Measurement day 1-7 | 4A | 8+ |
| INT4_Tmax_1-7 | Time of longest continuous 'INT4' segment. Measurement day 1-7 | 4A | 8+ |
| INT4_NBreaks_1-7 | Number of breaks of INT4 postures.Measurement day 1-7 | 4A | 8+ |
| INT34_1-7 | Time spent on activities classified as moderate and vigorous physical activity. Measurement day 1-7 | 4A | 8+ |
| INT34_T30min_1-7 | Total time duration of segments longer than 30 minutes of 'INT34' . Measurement day 1-7 | 4A | 8+ |
| INT34_N30min_1-7 | Number of segments longer than 30 minutes of 'INT34' . Measurement day 1-7 | 4A | 8+ |
| INT34_Tmax_1-7 | Time of longest continuous 'INT34' segment. Measurement day 1-7 | 4A | 8+ |
| INT34_NBreaks_1-7 | Number of breaks of INT3 or INT4 postures. Measurement day 1-7 | 4A | 8+ |
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