Table of Contents

Paper and manuscript references

In this section you can find a list of references you are asked to include in your publication if you have used the data. You will be able to find both the references for used phenotypic data as well as genetic data.

Phenotypic data

Covid

We kindly ask you to attach the following banner to your manuscript using Covid data from the Lifelines Corona Research. Please see this publication as an example on how to use the banner https://pubmed.ncbi.nlm.nih.gov/29198723/,you could add ‘Lifelines Corona Research Initiative’ to the author list. The list below gives a detailed description of the authors involved and their affiliation.

Lifelines Corona Research Initiative: HM Boezen1, Jochen O. Mierau2,3, H. Lude Franke4, Jackie Dekens4,6, Patrick Deelen4, Pauline Lanting4, Judith M. Vonk1, Ilja Nolte1, Anil P.S. Ori4,5, Annique Claringbould4, Floranne Boulogne4, Marjolein X.L. Dijkema4, Henry H. Wiersma4, Robert Warmerdam4, Soesma A. Jankipersadsing4, Irene van Blokland4,7.

1 Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
2 Faculty of Economics and Business, University of Groningen, Groningen, The Netherlands
3 Aletta Jacobs School of Public Health, Groningen, The Netherlands
4 Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
5 Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
6 Center of Development and Innovation, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
7 Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands

FFQ sum scores

FFQ sum scores data are generated by the Department of Human Nutrition, WUR, which will be informed by Lifelines about requests for data from other researchers. Please refer to the following reference in publications on this data: “Siebelink, E., Geelen, A., & de Vries, J. H. (2011). Self-reported energy intake by FFQ compared with actual energy intake to maintain body weight in 516 adults. British journal of nutrition, 106(2), 274-281.”

Gender index

Gender index derivate data is generated by the University Medical Center Groningen, UMCG. Please refer to the following reference in publications on this data: “Ballering A.V., Bonvanie I.J., olde Hartman T.C., Monden R., Rosmalen J.G.M. (2020) Gender and sex independently associate with common somatic symptoms and lifetime prevalence of chronic disease. Social Science & Medicine.”

Lifelines Diet Score

Lifelines Diet Score (LLDS) derivate data are generated by the University Medical Center Groningen, UMCG, which will be informed by Lifelines about requests for data from other researchers. Please refer to the following reference in publications on this data: “Vinke, P. C., Corpeleijn, E., Dekker, L. H., Jacobs, D. R., Navis, G., & Kromhout, D. (2018). Development of the food-based Lifelines Diet Score (LLDS) and its application in 129,369 Lifelines participants. European Journal of Clinical Nutrition, 72(8), 1111-1119.”

Sleep indices

Sleep index derivative data are generated by the Erasmus Medical Center, Erasmus MC. Please refer to the following reference in publications on this data: “Kocevska, D., Lysen, T. S., Dotinga, A., Koopman-Verhoeff, M. E., Luijk, M. P., Antypa, N., … & Tiemeier, H. (2020). Sleep characteristics across the lifespan in 1.1 million people from the Netherlands, United Kingdom and United States: a systematic review and meta-analysis. Nature human behaviour, 1-10.”

Vitamin D data

Vitamin D data are generated by the Department of Cardiology (UMCG). Rudolf de Boer has agreed that these data may be used for the purpose of the research questions as stated in the researcher's proposal. In publications on these data a reference should be made to Meems et al. ‘Low levels of vitamin D are associated with mutimorbidity: Results from the Lifelines Cohort Study.’ Annals of Medicine 2015; 47: 474-481.

Genetic data

CytoSNP

Genetic (CytoSNP) data with 1KG and GoNL imputations data are generated by the Genomics Coordination Center, UMCG. Two co-authorships need to be included in the publication in coordination with Dr Morris Swertz, Head of the Genomics Coordination Center, UMCG.

Reference: Genome of the Netherlands Consortium. Whole-genome sequence variation, population structure and demographic history of the Dutch population. Nat Genet. 2014 Aug;46(8):818-25.

Lifelines DEEP

For this proposal, genetic data from Lifelines-DEEP are requested. This data is generated by the Genetics department under supervision of prof. dr. Lude Franke (l.h.franke@umcg.nl). We kindly ask you to attach the following banner and acknowledgement to your manuscript using DEEP data from the Lifelines DEEP Cohort. Please see this publication as an example on how to use the banner https://pubmed.ncbi.nlm.nih.gov/29198723/, you can add ‘Lifelines DEEP Cohort’ to the author list. The list below gives a detailed description of the authors involved and their affiliation.

Lifelines DEEP Cohort: Lude Franke1, Sasha Zhernakova1, Jingyuan Fu1, Morris Swertz1, Cisca Wijmenga1

1 Department of Genetics, University of Groningen, University Medical Center Groningen, The Netherlands

Acknowledgements Generation and management of Lifelines Deep data is supported by an ERC Advanced Grant to Cisca Wijmenga, ERC Starting Grant to Lude Franke and Sasha Zhernakova, a VIDI grant to Lude Franke, Jingyuan Fu and Morris Swertz and several other subsidies from NWO / ZonMW.

Reference (methylation): Bonder et al, Nat. Genet. (2017) Disease variants alter transcription factor levels and methylation of their binding sites; doi: 10.1038/ng.3721