====== Covid-19 questionnaires (COVQ) ====== The Lifelines Covid-19 (COVQ) project consists of a series of [[additional assessments|additional questionnaires]] to be filled in by adult [[start|Lifelines]] [[cohort|participants]] during the [[https://en.wikipedia.org/wiki/Coronavirus_disease_2019|Covid-19]] pandemic of 2020.\\ The project is a collaboration between [[https://www.lifelines.nl/corona-onderzoek|Lifelines]], the[[https://www.umcg.nl|University Medical Centre Groningen]], the [[https://www.rug.nl|University of Groningen]] and the [[https://www.rug.nl/aletta|Aletta Jacobs School of Public Health]].\\ The aim of the project is to assess the possible multifactorial causes of developing serious symptoms in response to an infection with Covid-19, as well as the impact of the [[https://en.wikipedia.org/wiki/Pandemic|pandemic]] and the associated [[https://en.wikipedia.org/wiki/Quarantine|quarantine]] on physical and mental health and socio-economic status in the general population. ===== Protocol ===== Digital questionnaires were sent out weekly (later: bi-weekly and monthly) to all adult Lifelines participants with a known e-mail address. COVQ1 and COVQ2 contain “baseline” questions to obtain important current basic characteristics of all respondents.\\ All follow-up questionnaires (COVQ3 to COVQ12) contain a basic set of questions, complemented with a set of variable additional questions.\\ COVQ10 was a longer ‘special’ questionnaire. Only some of the basic questions were added. New topics were added about corona adjustments policies, work, holidays and resilience. ===== Reference paper ===== * Mc Intyre K et al. (2021) [[https://bmjopen.bmj.com/content/11/3/e044474.long|Lifelines COVID-19 cohort: investigating COVID-19 infection and its health and societal impacts in a Dutch population-based cohort]]. BMJ Open 11(3):e044474. Other papers from the Lifelines COVID-19 initiative: * van Blokland IV et al. (2021) [[https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0255402|Using symptom-based case predictions to identify host genetic factors that contribute to COVID-19 susceptibility]]. PLoS ONE 16(8): e0255402 * Ballering AV et al. (2022) [[https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)01214-4/fulltext|Persistence of somatic symptoms after COVID-19 in the Netherlands: an observational cohort study]]. Lancet 400(10350):452-461 * Warmerdam CAR et al. (2022) [[https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1010135|Increased genetic contribution to wellbeing during the COVID-19 pandemic]]. PLoS Genet 18(5):e1010135 * Ori, A et al. (2023) [[https://www.sciencedirect.com/science/article/pii/S0165032722013003?via%3Dihub|Longitudinal analyses of depression, anxiety, and suicidal ideation highlight greater prevalence in the northern Dutch population during the COVID-19 lockdowns]]. J Affect Disord 323:62-70 ===== Timeline & Response ===== In April 2020, Lifelines started to send out the first questionnaires to ~130,000 adult Lifelines [[cohort|participants]]. Follow-up questionnaires were send out on a weekly (and later bi-weekly and monthly) basis. * Questionnaire 1-7: ~130.000 participants were invited * Questionnaire 8-17: ~110,000 participants were invited * Questionnaire 18-23: ~65,500 participants were invited (selection: at least 2 previous COVQ questionnaires filled in) * Questionnaire 24-29: ~50,000 participants were invited (selection: at least 1 COVQ questionaires filled in in 2021, and no "unsubscribe" e-mail sent) ^ COVQ ^ Date ^ Response ^ Response rate ^ | 1 | 30-03 to 23-04-2020 | ~53,000 | 41% | | 2 | 02-04 to 06-05-2020 | ~51,000 | 39% | | 3 | 12-04 to 06-05-2020 | ~50,000 | 38% | | 4 | 16-04 to 13-05-2020 | ~47,000 | 36% | | 5 | 19-04 to 20-05-2020 | ~45,000 | 35% | | 6 | 28-04 to 27-05-2020 | ~43,000 | 33% | | 7 | 15-05 to 29-05-2020 | ~45,000 | 34% | | 8* | 23-05 to 24-06-2020 | ~38,000 | 34% | | 9 | 11-06 to 29-06-2020 | ~37,000 | 33% | | 10 | 07-07 to 29-07-2020 | ~33,000 | 30% | | 11 | 10-07 to 05-08-2020 | ~35,000 | 32% | | 12 | 24-07 to 02-09-2020 | ~36,000 | 32% | | 13 | 08-09 to 30-09-2020 | ~35,000 | 32% | | 14 | 13-10 to 04-11-2020 | ~34,000 | 31% | | 15 | 02-11 to 26-11-2020 | ~34,000 | 31% | | 15b | 15-11 to 10-12-2020 | ~33,000 | 30% | | 16 | 02-12 to 21-12-2020 | ~31,000 | 28% | | 16b | 08-12 to 05-01-2021 | ~32,000 | 29% | | 17 | 05-01 to 08-02-2021 | ~34,000 | 31% | | 18* | 25-02 to 25-03-2021 | ~32,000 | 49% | | 19 | 29-03 to 22-04-2021 | ~29,000 | 45% | | 20 | 26-04 to 20-05-2021 | ~29,000 | 44% | | 21 | 25-05 to 18-06-2021 | ~29,000 | 45% | | 22 | 04-07 to 30-07-2021 | ~24,000 | 36% | | 23 | 11-10 to 04-11-2021 | ~23,000 | 37% | | 24* | 20-12-21 to 12-01-2022 | ~25,000 | 48% | | 25 | 28-02 to 24-03-2022 | ~20,000 | 38% | | 26 | 11-04 to 04-05-2022 | ~20,000 | 40% | | 27 | 31-05 to 27-06-2022 | ~19,000 | 36% | | 28 | 11-07 to 03-08-2022 | ~18,000 | 36% | | 29 | 29-09 to 19-10-2022 | ~21,000 | 42% | ^ Number of participants ^ First 19 questionnaires completed? ^ | ~77,000 | 1 of 19 | | ~66,000 | 2 of 19 | | ~60,000 | 3 of 19 | | ~55,000 | 4 of 19 | | ~51,000 | 5 of 19 | | ~48,000 | 6 of 19 | | ~45,000 | 7 of 19 | | ~42,000 | 8 of 19 | | ~40,000 | 9 of 19 | | ~37,500 | 10 of 19 | | ~35,500 | 11 of 19 | | ~33,000 | 12 of 19 | | ~31,000 | 13 of 19 | | ~28,500 | 14 of 19 | | ~26,500 | 15 of 19 | | ~24,000 | 16 of 19 | | ~21,000 | 17 of 19 | | ~17,000 | 18 of 19 | | ~11,000 | 19 of 19 | ===== Variables ===== COVQ assessed variables in the following corona-specific subsections: * [[Demographics]]: * [[Work & income (Covid-19)]] (incl. work situation and job loss of participants and family members) * [[Diseases & symptoms]]: * [[Covid-19 infection]] (infection with Covid-19 itself) * [[Chronic diseases (Covid-19)]] (participant's history of chronic diseases) * [[Symptoms (Covid-19)]] (all types of symptoms suffered during the Corona crisis) * [[Lifestyle & environment]]: * [[Lifestyle (Covid-19)]] (incl. diet, activity, smoking, alcohol use, and compliance with Covid-measures) * [[Quarantine (Covid-19)]] (compliance with quarantine/self-isolation guidelines) * [[Medical treatment]]: * [[Medication (Covid-19)]] (extensive questionnaire on medication use during the corona crisis) * [[Vaccination (Covid-19)]] (questions about vaccination with the covid-19 vaccins) * [[Mental health]]: * [[Mental health (Covid-19)]] (items derived from the [[mini neuropsychiatric interview|MINI]]) + memory * [[Social functioning (Covid-19)]] (incl. social isolation, connection, feelings about society) * [[Wellbeing & subjective health]] * [[Wellbeing (Covid-19)]] (quality of life during the corona crisis) In addition, various variables were collected in general subsections: * [[Demographics]]: [[Personal data]] (1 item on response date) * [[Demographics]]: [[Family composition]] (1 item on pregnancy) * [[Demographics]]: [[Household composition]] (children living at home) * [[Demographics]]: [[Education]] (home-schooling) * [[Diseases & symptoms]]: [[Infectious diseases]] (participant's history of infectious diseases) * [[Medical treatment]]: [[Vaccination]] * [[Medical treatment]]: [[Treatment (general)]] (postponement of medical treatments due to the corona crisis) * [[Physical state]]: [[Anthropometry (Self-reported)]] (body weight) * [[Reproduction & development]]: [[Menstruation]]