====== Lifelines Child Cohort ======

Our ~15.000 underage participants (at [[1A|baseline]]) are an important part of the [[start|Lifelines]] cohort.\\ 
Children were recruited via their parents. Depending on their age, children participated in various measurements and questionnaires over time.\\


{{:timeline_children.png?direct&600|}}

===== Children at 1A =====

At [[1A|baseline]], children participated in the following measurements/questionnaires:
  * [[Anthropometry|Anthropometric measures]] (8-17 years) -> [[1A Visit 1]]
  * [[Blood pressure]] (8-17 years) -> [[1A Visit 1]]
  * [[ECG|12-lead electrocardiogram]] (13-17 years) -> [[1A Visit 1]]
  * [[Pulmonary function test]] (8-17 years) -> [[1A Visit 1]]
  * [[Blood samples|Blood sample collection]] (8-17 years) -> [[1A Visit 2]]
  * [[Urine samples|Urine sample collection]] (8-17 years) -> [[1A Visit 2]]
  * [[1A Birth questionnaire]] (0-17 years, filled in by the parents)
  * [[1A General questionnaire]] (4-17 years, filled in by the parents)
  * [[1A Behavior questionnaire]] (8-17 years, filled in by the parents)
  * [[1A Food questionnaire]] (8-12 years, filled in by the parents)
  * [[1A Youth questionnaire]] (13-17 years, self-report)

Age distribution for [[1A]] Child participants:
^ Assessment                              ^ 0-3 years  ^ 4-7 years  ^ 8-12 years  ^ 13-17 years  ^
| [[1A Birth questionnaire|Birth]]        | ~2400      | ~2800      | ~5500       | ~3900        |
| [[1A General questionnaire|General]]    |            | ~2700      | ~5500       | ~3900        |
| [[1A Behavior questionnaire|Behavior]]  |            |            | ~5300       | ~3900        |
| [[1A Food questionnaire|Food]]          |            |            | ~4100       | ~3600        |
| [[1A Youth questionnaire|Youth]]        |            |            |             | ~4000        |
| [[1A Visit 1]]                          |            |            | ~5600       | ~4100        |
| [[1A Visit 2]]                          |            |            | ~5400       | ~4100        |

Underage participants did **not receive any follow-up questionnaires** between assessments [[1A]] and [[2A]], unless they turned 18 (n = ~780).

===== Children at 2A =====

In assessment [[2A]], children participated in the following measurements/questionnaires:

  * [[Anthropometry|Anthropometric measures]] (8-17 years) -> [[2A Visit 1]]
  * [[Blood pressure]] (8-17 years) -> [[2A Visit 1]]
  * [[ECG|12-lead electrocardiogram]] (13-17 years) -> [[2A Visit 1]]
  * [[Jump test]] (8-17 years) -> [[2A Visit 1]]
  * [[CogState]] (13-17 years) -> [[2A Visit 1]]
  * [[Pulmonary function test]] (8-17 years) -> [[2A Visit 1]]
  * [[Blood samples|Blood sample collection]] (8-17 years) -> [[2A Visit 2]]
  * [[Urine samples|Urine sample collection]] (8-17 years) -> [[2A Visit 2]]
  * [[2A Child questionnaire]] (4-12 years, filled in by the parents)
  * [[2A Youth questionnaire]] (13-17 years, self-report)

Age distribution for [[2A]] Child participants:
^ Assessment                  ^ 0-3 years  ^ 4-7 years  ^ 8-12 years  ^ 13-17 years  ^
| [[2A Child questionnaire]]  |            | ~2300      | ~2900       | ~300         |
| [[2A Youth questionnaire]]  |            |            |             | ~2600        |
| [[2A Visit 1]]              |            |            | ~3000       | ~3600        |
| [[2A Visit 2]]              |            |            | ~2800       | ~3400        |

===== Children at 3A =====

In assessment [[3A]], children participated in the following measurements/questionnaires:

  * [[Anthropometry|Anthropometric measures]] (8-17 years) -> [[3A Visit 1]]
  * [[Blood pressure]] (8-17 years) -> [[3A Visit 1]]
  * [[ECG|12-lead electrocardiogram]] (13-17 years) -> [[3A Visit 1]]
  * [[CogState]] (13-17 years) -> [[3A Visit 1]]
  * [[Pulmonary function test]] (13-17 years) -> [[3A Visit 1]]
  * [[Blood samples|Blood sample collection]] (8-17 years) -> [[3A Visit 2]]
  * [[Urine samples|Urine sample collection]] (8-17 years) -> [[3A Visit 2]]
  * [[3A Child questionnaire]] (4-12 years, filled in by the parents)
  * [[3A Youth questionnaire]] (13-17 years, self-report)











===== Children in Additional Assessments =====

Various [[additional assessments]] include underage participants:
  * [[DAG3]] (microbiome)
  * [[UGLI]] (genotyping)
  * [[NEXT]] (birth cohort)
  * [[ADHQ]] (ADHD questionnaire)
  * [[BLUQ]] (screen use questionnaire)
  * [[DCDQ]] (motor development questionnaire)