====== Blood sample analyses ====== The following variables were assessed in the plasma of fresh [[blood samples]] collected from [[start|Lifelines]] participants during [[1A Visit 2]], [[2A Visit 2]] and [[3A Visit 2]] ([[sections|section]]: [[physical state]]).\\ Assessments were performed at the laboratory center of the [[https://www.umcg.nl|University Medical Center Groningen]] that is [[https://www.umcg.nl/-/afdeling/laboratoriumgeneeskunde/informatie-voor-professionals|certified]] according to NEN-EN-ISO 9001:2015 and NEN-EN-ISO 15189:2012 standards.\\ For more information about individual assays, see [[https://www.umcg.nl/bepalingenwijzer|here]].\\ Note that additional analyses were performed on [[urine analyses|urine]] samples collected on the same day.\\ [[hscrp|High-sensitivity CRP]] was analysed using 3 methods, follow the link for more detail. | **English** | **Code** | **Variable** | **N at [[1A Visit 2|1A]]** | **N at [[2A Visit 2|2A]]** | **N at [[3A Visit 2|3A]]** | **N at 4A (ongoing)** | **Age** | **Report to GP?** | | Has the participant been fasting? | fasting_participant_all_q_1 | NUCHTER | ~156k | ~111k | ~82k | 100+ | 8+ | | | the blood sample was obtained within 24h (before or after) the 24h [[urine samples|urine sample]] | blood_urine24h_all_m_1 | BL_24H | ~131k | ~99k | ~78k | 100+ | 18+ | | | the blood sample was obtained within 24h (before or after) the early morning spot [[urine samples|urine sample]] | blood_urineems_all_m_1 | BL_EMS | ~42k | - | - | - | 18+ | | | the blood sample was obtained within 24h (before or after) the timed overnight [[urine samples|urine sample]] | blood_urineto_all_m_1 | BL_TO | ~7.5k | ~5.2k | ~1.6k | - | 8 – 17 | | | Basophilic Granulocytes in EDTA Sysmex (10E9/L) | basoconc_result_all_m_1 | BA | ~156k | ~110k | ~82k | 100+ | 8+ | | | Basophilic Granulocytes in EDTA Sysmex (%) | basoperc_result_all_m_1 | BAP | ~156k | ~75k | ~82k | 100+ | 8+ | | | Erythrocytes in EDTA Sysmex (10E12/L) | erythrocyte_result_all_m_1 | ER | ~156k | ~110k | ~82k | 100+ | 8+ | yes | | Erythroblasts in EDTA Sysmex (10E9/L) | erythroblconc_result_all_m_1 | EBT | - | ~110k | ~82k | 100+ | 8+ | | | Erythroblasts in EDTA Sysmex (%) | erythroblperc_result_all_m_1 | NRBP | - | ~100 | ~82k | 100+ | 8+ | | | Eosinophilic Granulocytes in EDTA Sysmex (10E9/L) | eosinoconc_result_all_m_1 | EO | ~156k | ~110k | ~82k | 100+ | 8+ | | | Eosinophilic Granulocytes in EDTA Sysmex (%) | eosinoperc_result_all_m_1 | EOP | ~156k | ~75k | ~82k | 100+ | 8+ | | | Immature granulocytes in EDTA Sysmex (10E9/L) | imgranconc_result_all_m_1 | IG | - | ~110k | ~82k | 100+ | 8+ | | | Immature granulocytes in EDTA Sysmex (%) | imgranperc_result_all_m_1 | IGP | - | ~75k | ~82k | 100+ | 8+ | | | Leukocytes in EDTA Sysmex (10E9/L) | leukocyte_result_all_m_1 | LE | ~156k | ~110k | ~82k | 100+ | 8+ | yes | | Lymphocytes in EDTA Sysmex (10E9/L) | lymphoconc_result_all_m_1 | LY | ~156k | ~110k | ~82k | 100+ | 8+ | | | Lymphocytes in EDTA Sysmex (%) | lymphoperc_result_all_m_1 | LYP | ~156k | ~75k | ~82k | 100+ | 8+ | | | Mononuclear Cells in EDTA Sysmex (10E9/L) | monoconc_result_all_m_1 | MO | ~156k | ~110k | ~82k | 100+ | 8+ | | | Mononuclear Cells in EDTA Sysmex (%) | monoperc_result_all_m_1 | MOP | ~156k | ~75k | ~82k | 100+ | 8+ | | | Neutrophilic Granulocytes in EDTA Sysmex (10E9/L) | neutroconc_result_all_m_1 | GR | ~156k | ~110k | ~82k | 100+ | 8+ | | | Neutrophilic Granulocytes in EDTA Sysmex (%) | neutroperc_result_all_m_1 | GRP | ~156k | ~75k | ~82k | 100+ | 8+ | | | Thrombocytes in EDTA Sysmex (10E9/L) | thrombocyte_result_all_m_1 | TR | ~156k | ~110k | ~82k | 100+ | 8+ | yes | | Reticulocytes in EDTA Sysmex (10E9/L) | reticuloconc_result_all_m_1 | RE | - | ~29k | - | 100+ | 8+ | | | Reticulocytes in EDTA Sysmex (‰) | reticuloprom_result_all_m_1 | REP | - | ~29k | - | 100+ | 8+ | | | Platelet large cell ratio in EDTA Sysmex | | PLCR | - | - | ~82k | 100+ | 8+ | | | Hematocrit in EDTA Sysmex (L/L) | hematocrit_result_all_m_1 | HT | ~156k | ~110k | ~82k | 100+ | 8+ | yes | | Hemoglobin in EDTA Sysmex (mmol/L) | hemoglobin_result_all_m_1 | HB | ~156k | ~110k | ~82k | 100+ | 8+ | yes | | HbA1c in EDTA Sysmex (%) | hba1cperc_result_all_m_1 | HBAC | ~156k | ~110k | ~82k | 100+ | 8+ | yes | | HbA1c in EDTA Sysmex (mmol/mol) | hba1cconc_result_all_m_1 | HB1C | ~156k | ~110k | ~82k | 100+ | 8+ | | | Mean corpuscular hemoglobin concentration (mmol/L) | mcc_result_all_m_1 | MCC | - | ~110k | ~82k | 100+ | 8+ | | | Mean corpuscular hemoglobin (amol) | mch_result_all_m_1 | MCH | - | ~110k | ~82k | 100+ | 8+ | | | Mean corpuscular volume (fl) | mcv_result_all_m_1 | MCV | - | ~110k | ~82k | 100+ | 8+ | | | Plateletcrit (L/L) | pct_result_all_m_1 | PCT | - | | ~82k | 100+ | 8+ | | | Red cell distribution width (%) | rdw_result_all_m_1 | RDW | - | ~110k | ~82k | 100+ | 8+ | | | Surface of the red cell distribution width (%) | rdws_result_all_m_1 | | | | ~82k | 100+ | 8+ | | | Mean platelet volume (fl) | mpv_result_all_m_1 | MPV | - | ~75k | ~82k | 100+ | 8+ | | | Platelet distribution width (%) | pdw_result_all_m_1 | PDW | - | ~75k | ~82k | 100+ | 8+ | | | Reticulocyte hemoglobin equivalent (amol) | rethe_result_all_m_1 | RETH | - | ~29k | - | - | 8+ | | | Difference between reticulocyte and erythrocyte hemoglobin content (amol) | deltahe_result_all_m_1 | RETD | - | ~29k | - | - | 8+ | | | Immature platelet fraction (%) | ipf_result_all_m_1 | OTBF | - | ~29k | - | - | 8+ | | | Immature reticulocyte fraction (%) | irf_result_all_m_1 | OREF | - | ~29k | - | - | 8+ | | | Estimated glomerular filtration rate (ml/min/1.73 m²) | | EGFR | - | - | - | 100+ | 8+ | | | Glucose in NaF (mmol/L) | glucose_result_all_m_1 | GLU | ~156k | ~110k | ~82k | 100+ | 8+ | yes | | Potassium in heparin (mmol/L) | potassium_result_all_m_1 | K | ~156k | ~110k | ~82k | 100+ | 8+ | yes | | Creatinine in heparin (umol/L) | creatinine_result_all_m_1 | BKR | ~156k | ~110k | ~82k | 100+ | 8+ | yes | | Chloride in heparin (mmol/L) | chloride_result_all_m_1 | CL | - | ~110k | ~82k | 100+ | 8+ | | | Cholesterol total in heparin (mmol/L) | cholesterol_result_all_m_1 | CHO | ~156k | ~110k | ~82k | 100+ | 8+ | yes | | HDL Cholesterol in heparin (mmol/L) | hdlchol_result_all_m_1 | HDC | ~156k | ~110k | ~82k | 100+ | 8+ | yes | | LDL Cholesterol in heparin (mmol/L) | ldlchol_result_all_m_1 | LDC | ~156k | ~110k | ~82k | 100+ | 8+ | yes | | Triglycerides in heparin (mmol/L) | triglyceride_result_all_m_1 | TGL | ~156k | ~110k | ~82k | 100+ | 8+ | yes | | Sodium in heparin (mmol/L) | sodium_result_all_m_1 | NA | ~59k | ~110k | ~82k | 100+ | 8+ | yes | | Urea in heparin (mmol/L) | urea_result_all_m_1 | UR | ~59k | - | ~82k | 100+ | 8+ | | | ALAT in heparin (U/L) | alat_result_all_m_1 | ALT | ~59k | - | - | 100+ | 8+ | yes | | ASAT in heparin (U/L) | asat_result_all_m_1 | AST | ~59k | - | - | 100+ | 8+ | yes | | Albumin in heparin (g/L) | albumin_result_all_m_1 | BALB | ~59k | - | - | - | 8+ | | | Alkaline Phosphatase in heparin (U/L) | alkphos_result_all_m_1 | AF | ~59k | - | - | - | 8+ | yes | | Calcium in heparin (mmol/L) | calcium_result_all_m_1 | CA | ~59k | - | - | - | 8+ | yes | | Gamma-GT in heparin (U/L) | gammagt_result_all_m_1 | GGT | ~59k | - | - | - | 8+ | yes | | Phosphate in heparin (mmol/L) | phosphate_result_all_m_1 | FOS | ~59k | - | - | - | 8+ | | | Uric acid in heparin (mmol/L) | uricacid_result_all_m_1 | UZ | ~59k | - | - | - | 8+ | | | TSH in heparin (mU/L) | tsh_result_all_m_1 | TSHD | ~41k | - | - | 100+ | 8+ | | | Free T3 in heparin (pmol/L) | t3free_result_all_m_1 | FT3 | ~41k | - | - | 100+ | 8+ | | | Free T4 in heparin (pmol/L) | t4free_result_all_m_1 | FT4 | ~41k | - | - | 100+ | 8+ | | | CTD Screen (Ratio) | ctdscreen_result_all_m_1 | CTDS | ~40k | - | - | - | 18+ | | | Anti-CCP (U/mL) | anticcp_result_all_m_1 | CCP | ~40k | - | - | - | 18+ | | | Apolipo A1 in heparin (g/L) | apolipoa1_result_all_m_2 | HAL1 | ~35k | - | - | - | 8+ | | | Apolipo B100 in heparin (g/L) | apolipob100_result_all_m_2 | HALB | ~35k | - | - | - | 8+ | | | Apolipo A1 in serum (g/L) | apolipoa1_result_all_m_1 | ALPA | ~8k | - | - | - | 8+ | | | Apolipo B100 in serum (g/L) | apolipob100_result_all_m_1 | ALPB | ~8k | - | - | - | 8+ | | | [[hsCRP]] in serum (mg/L) | hscrp_result_all_m_1 | SCRP | ~8k | - | ~82k | 100+ | 8+ | | | [[hsCRP]] in heparin (mg/L) | hscrp_result_all_m_3 | CRPH | ~1k | ~500 | - | 100+ | 8+ | | | [[hsCRP]] in heparin (mg/L) | hscrp_result_all_m_2 | LCRP | ~49k | - | - | 100+ | 8+ | | | Magnesium in heparin (mmol/L) | magnesium_result_all_m_1 | MG | - | ~2k | - | 100+ | 8+ | | | Anti-dsDNA (U/L) | antidsdna_result_all_m_1 | DDNA | ~1k | - | - | - | 18+ | | | SSA preg (U/mL) | ssapreg_result_all_m_1 | SSA | ~1k | - | - | - | 18+ | | | Basophilic Granulocytes in blood cell count (%) | basocount_result_all_m_1 | BAS | ~3k | - | - | - | 8+ | | | Eosinophilic Granulocytes in blood cell count (%) | eosinocount_result_all_m_1 | EOS | ~3k | - | - | - | 8+ | | | Lymphocytes in blood cell count (%) | lymphocount_result_all_m_1 | LYM | ~3k | - | - | - | 8+ | | | Mononuclear Cells in blood cell count (%) | monocount_result_all_m_1 | MON | ~3k | - | - | - | 8+ | |