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====== Depression & Anxiety (LIDAS) ======

The Lifetime Depression Assessment Self-Report (LIDAS) digital questionnaire is largely based on the [[https://www.who.int|WHO]]'s Composite International Diagnostic Interview short form ([[https://www.hcp.med.harvard.edu/wmhcidi|CIDI-sf]]) for depression, and is used to identify persons who have or have not been depressed in their lifetime.\\ 
The LIDAS has been developed for online use and is validated against a full CIDI for depression, with sensitivity and specificity >80% ((Bot et al., Validity of LIDAS (LIfetime Depression Assessment Self-report): a self-report online assessment of lifetime major depressive disorder. Psychol Med. 2017 Jan;47(2):279-289 **-> please cite this paper when using the LIDAS data**)) ((Fedko et al. Measurement and genetic architecture of lifetime depression in the Netherlands as assessed by LIDAS (Lifetime Depression Assessment Self-report). Psychol Med. 2020 Jan;51(8): 1-10 **-> please cite this paper when using the LIDAS data**)) 

The LIDAS was implemented in [[start|Lifelines]] in the context of an [[additional assessments|additional assessment]]: [[BIONIC]], once in its original form ([[BIONIC|DEPQ]]), and once extended with several additional questions ([[BIONIC|DEAQ]])((van Loo et al., The structure of the symptoms of major depression: Factor analysis of a lifetime worst episode of depressive symptoms in a large general population sample. J Affect Disord 307: 115-124 **-> please cite this paper when using the DEAQ data**)). In addition, parts of the LIDAS have been included in the [[additional assessments|additional assessment]] [[MHDQ]].\\
Note that recent depression and anxiety is assessed in Lifelines participants using the [[Mini Neuropsychiatric Interview]] in assessment [[1A Visit 1|1A]], [[2A Visit 1|2A]], and [[3A]] (see [[sections|section]] [[mental health]]).

===== Variables =====
=== General questions===

| **Label English**                                                                                          | **Label Dutch**                                                                                | **Code**                    | **Variable**  | **Assessment**        | **Age**  |
| are you at least once a week, in your own free time, physically active to the extent that it makes you sweat?  | bent u minstens een keer per week in uw vrije tijd zo lichamelijk actief dat u ervan gaat zweten?  | lidas_activity_adu_q_1      | activity      | [[BIONIC|DEPQ+DEAQ]]  | 18+      |
| do you currently smoke, or have you smoked in the last month?                                                  | rookt u nu, of hebt u de afgelopen maand nog gerookt?                                              | smoking_current_adu_q_1_v2  | roken         | [[BIONIC|DEPQ+DEAQ]]  | 18+      |

===Major depressive disorder===
| **Label English**                                                                                                                                                                                                                                            | **Label Dutch**                                                                                                                                                                                                                                                 | **Code**               | **Variable**  | **Assessment**                 | **Age**  |
| have you ever had a time in your life when you felt sad, empty, or depressed for two weeks or longer?                                                                                                                                                        | hebt u zich ooit wel eens twee weken of langer somber, leeg of depressief gevoeld?                                                                                                                                                                              | lidas_mdd_adu_q_01     | depsymp1      | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| think about a period of two weeks in your life when these feelings were worst. during this period of two weeks, how often did you feel this way?                                                                                                             | denk aan de periode van twee weken in uw leven waarin deze gevoelens het ergst waren. tijdens deze periode van twee weken, hoe vaak voeldu u zich zo?                                                                                                           | lidas_mdd_adu_q_01_a   | depsymp2      | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| during this period that you felt sad, empty or depressed, did you ever have a period lasting two weeks or more when you lost interest in most things like hobbies, work, or activities that usually give you pleasure?                                       | tijdens de periode dat u zich somber, leeg of depressief voelde, hebt u toen ooit twee weken of langer gehad waarin u uw interesse verloor voor de meeste dingen, zoals werk, hobby's en andere dingen waar u gewoonlijk plezier aan beleeft?                   | lidas_mdd_adu_q_01_b   | depsymp5      | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| think about the period of two weeks in your life when your loss of interest was worst. during this period of two weeks, how often did you feel this way?                                                                                                     | denk aan de periode van twee weken in uw leven waarin het verlies van interesse voor dingen het ergst was. tijdens deze periode van twee weken, hoe vaak voelde u zich zo?                                                                                      | lidas_mdd_adu_q_01_c   | depsymp6      | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| have you ever had a time in your life lasting two weeks or more when you lost your interest in most things like hobbies, work, or activities that usually give you pleasure?                                                                                 | hebt u ooit twee weken of langer gehad waarin u uw interesse verloor voor de meeste dingen, zoals werk, hobby's en andere dingen waar u gewoonlijk plezier aan beleeft?                                                                                         | lidas_mdd_adu_q_02     | depsymp3      | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| think about the period of two weeks in your life when your loss of interest was worst. during this period of two weeks, how often did you feel this way?                                                                                                     | denk aan de periode van twee weken in uw leven waarin het verlies van interesse voor dingen het ergst was. tijdens deze periode van twee weken, hoe vaak voelde u zich zo?                                                                                      | lidas_mdd_adu_q_02_a   | depsymp4      | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| did you have less appetite than usual almost every day? / during this period of at least two weeks in which you felt sad, empty, or depressed or you lost your interest in things:                                                                           | had u toen bijna dagelijks minder eetlust dan gewoonlijk? / tijdens deze periode van tenminste twee weken waarin u zich somber, leeg of depressief voelde of uw interesse voor dingen verloor:                                                                  | lidas_mdd_adu_q_03_a1  | depweight1    | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| did you lose weight without trying to, as much as a kg per week for several weeks? / during this period of at least two weeks in which you felt sad, empty, or depressed or you lost your interest in things:                                                | viel u toen af zonder dat u dat probeerde, wel een kilo per week gedurende meerdere weken achtereen? / tijdens deze periode van tenminste twee weken waarin u zich somber, leeg of depressief voelde of uw interesse voor dingen verloor:                       | lidas_mdd_adu_q_03_a2  | depweight2    | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| how much weight did you lose in these weeks [kg]? / during this period of at least two weeks in which you felt sad, empty, or depressed or you lost your interest in things:                                                                                 | hoeveel viel u gedurende die weken af [kg]? / tijdens deze periode van tenminste twee weken waarin u zich somber, leeg of depressief voelde of uw interesse voor dingen verloor:                                                                                | lidas_mdd_adu_q_03_a3  | depweight3    | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| did you have a much larger appetite than usual almost every day for two weeks or more? / during this period of at least two weeks in which you felt sad, empty, or depressed or you lost your interest in things:                                            | had u toen twee weken of langer bijna dagelijks een veel grotere eetlust dan gewoonlijk? / tijdens deze periode van tenminste twee weken waarin u zich somber, leeg of depressief voelde of uw interesse voor dingen verloor:                                   | lidas_mdd_adu_q_03_b1  | depweight4    | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| did your eating increase so much that you gained weight, as much as a kg per week for several weeks? / during this period of at least two weeks in which you felt sad, empty, or depressed or you lost your interest in things:                              | nam uw eetlust zodanig toe dat u in gewicht aankwam, wel een kilo per week gedurende meerdere weken achtereen? / tijdens deze periode van tenminste twee weken waarin u zich somber, leeg of depressief voelde of uw interesse voor dingen verloor:             | lidas_mdd_adu_q_03_b2  | depweight5    | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| how much weight did you gain in these weeks [kg]? / during this period of at least two weeks in which you felt sad, empty, or depressed or you lost your interest in things:                                                                                 | hoeveel kwam u gedurende die weken aan [kg]? / tijdens deze periode van tenminste twee weken waarin u zich somber, leeg of depressief voelde of uw interesse voor dingen verloor:                                                                               | lidas_mdd_adu_q_03_b3  | depweight6    | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| did you have trouble sleeping almost every night, either trouble falling asleep, waking in the middle of the night or too early? / during this period of at least two weeks in which you felt sad, empty, or depressed or you lost your interest in things:  | had u toen ook bijna elke nacht slaapproblemen, d.w.z. moeite met inslapen, midden in de nacht of te vroeg wakker worden? / tijdens deze periode van tenminste twee weken waarin u zich somber, leeg of depressief voelde of uw interesse voor dingen verloor:  | lidas_mdd_adu_q_04_a1  | depsleep1     | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| did you wake up at least two hours before you wanted to, every day for at least two weeks? / during this period of at least two weeks in which you felt sad, empty, or depressed or you lost your interest in things:                                        | werd u twee weken of langer dagelijks minstens twee uur eerder wakker dan u wilde? / tijdens deze periode van tenminste twee weken waarin u zich somber, leeg of depressief voelde of uw interesse voor dingen verloor:                                         | lidas_mdd_adu_q_04_a2  | depsleep2     | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| did you sleep more than usual almost every day? / during this period of at least two weeks in which you felt sad, empty, or depressed or you lost your interest in things:                                                                                   | sliep u toen bijna dagelijks meer dan gewoonlijk? / tijdens deze periode van tenminste twee weken waarin u zich somber, leeg of depressief voelde of uw interesse voor dingen verloor:                                                                          | lidas_mdd_adu_q_04_b   | depsleep3     | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| did you talk or move more slowly than is normal for you almost every day, in a way that other people have noticed? / during this period of at least two weeks in which you felt sad, empty, or depressed or you lost your interest in things:                | sprak of bewoog u bijna dagelijks trager dan gewoon voor u is, zo dat andere mensen dit opgemerkt kunnen hebben? / tijdens deze periode van tenminste twee weken waarin u zich somber, leeg of depressief voelde of uw interesse voor dingen verloor:           | lidas_mdd_adu_q_05_a   | depmove1      | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| did you have to be moving all the time, that is, you could not sit still and paced up and down or could not keep your hands still when sitting, in a way that other people noticed? / during this period of at least two weeks…                              | moest u toen steeds maar bewegen, d.w.z. dat u niet stil kon zitten en maar op en neer bleef lopen, of dat u uw handen niet stil kon houden als u zat, zo dat andere mensen dit opgemerkt kunnen hebben? / tijdens deze periode van tenminste twee weken…       | lidas_mdd_adu_q_05_b   | depmove2      | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| did you lack energy or feel tired more than usual? / during this period of at least two weeks when you felt sad, empty or depressed or lost interest in things:                                                                                              | had u een gebrek aan energie of voelde u zich moe, meer dan gebruikelijk? / tijdens deze periode van tenminste twee weken waarin u zich somber, leeg of depressief voelde of uw interesse voor dingen verloor:                                                  | lidas_mdd_adu_q_06     | depsymp7      | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| during this period of two weeks, did you feel guilty or worthless?                                                                                                                                                                                           | tijdens deze periode van twee weken, voelde u zich schuldig of waardeloos?                                                                                                                                                                                      | lidas_mdd_adu_q_07     | depfunct3     | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| during this period of two weeks, did you have a lot more trouble concentrating than usual?                                                                                                                                                                   | tijdens deze periode van twee weken, had u toen veel meer moeite om u te concentreren dan gewoonlijk?                                                                                                                                                           | lidas_mdd_adu_q_08_a   | depfunct1     | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| during this period, were you able to make make up your mind about things that you ordinarily had no trouble deciding about?                                                                                                                                  | tijdens deze periode, was u in staat beslissingen te nemen over zaken waar u normaal zonder moeite over beslist?                                                                                                                                                | lidas_mdd_adu_q_08_b   | depfunct2     | [[BIONIC|DEPQ]]                | 18+      |
| during this period, were you **not** able to make make up your mind about things that you ordinarily had no trouble deciding about? (NB: altered to match the CIDI formulation)                                                                              | tijdens deze periode, was u **niet** in staat beslissingen te nemen over zaken waar u normaal zonder moeite over beslist? (NB: veranderd om aan de CIDI formulering te voldoen)                                                                                 | lidas_mdd_adu_q_08_b1  | depfunct2_1   | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| during this period of two weeks, did you think a lot about death: either your own, someone else's, or death in general?                                                                                                                                      | tijdens deze periode van twee weken, dacht u toen veel aan de dood: uw eigen, of die van iemand anders of de dood in het algemeen?                                                                                                                              | lidas_mdd_adu_q_09_a   | depfunct4     | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| During this period of at least two weeks in which you felt sad, empty, or depressed or you lost your interest in things:                                                                                                                                     | Denk bij de volgende vragen terug aan de periode van tenminste twee weken waarin u zich somber, leeg of depressief voelde of uw interesse voor dingen verloor (dezelfde periode waar u net vragen over hebt beantwoord). Tijdens deze periode...                |                        |               |                                | 18+      |
| ... did you feel so bad that you often thought about ending your life                                                                                                                                                                                        | ...voelde u zich zo slecht dat u er vaak aan dacht een einde aan uw leven te maken?                                                                                                                                                                             | lidas_mdd_adu_q_09_b   | depsymp8      | [[BIONIC|DEAQ]]                | 18+      |
| ... were your feelings of sadness other that the feelings you would have after the death of a loved one, or of a sad movie or story?                                                                                                                         | ...waren uw gevoelens van somberheid anders dan de gevoelens die u zou krijgen nadat een naaste overleed, of van een verdrietige film of een verdrietig verhaal?                                                                                                | lidas_mdd_adu_q_10     | depsymp9      | [[BIONIC|DEAQ]]                | 18+      |
| ... did you feel particularly bad right after getting up in the morning, but better later in the day?                                                                                                                                                        | ...voelde u zich vooral slecht vlak na het opstaan, maar beter later op de dag?                                                                                                                                                                                 | lidas_mdd_adu_q_11     | depsymp10     | [[BIONIC|DEAQ]]                | 18+      |
| ... did you have a reduced sex drive                                                                                                                                                                                                                         | ...had u veel minder zin in seks dan gewoonlijk?                                                                                                                                                                                                                | lidas_mdd_adu_q_12     | depsymp11     | [[BIONIC|DEAQ]]                | 18+      |
| ... could you enjoy positive events, such as winning something, being praised, or receiving compliments?                                                                                                                                                     | ...kon u plezier beleven aan positieve gebeurtenissen, zoals iets winnen, geprezen worden of complimenten krijgen?                                                                                                                                              | lidas_mdd_adu_q_13     | depsymp12     | [[BIONIC|DEAQ]]                | 18+      |
| ... did you feel irritated or angry most of the time?                                                                                                                                                                                                        | ...voelde u zich het grootste gedeelte van de tijd geïrriteerd of boos?                                                                                                                                                                                         | lidas_mdd_adu_q_14     | depsymp13     | [[BIONIC|DEAQ]]                | 18+      |
| ... did you feel hopeless about the future?                                                                                                                                                                                                                  | ...voelde u zich hopeloos over de toekomst?                                                                                                                                                                                                                     | lidas_mdd_adu_q_15     | depsymp14     | [[BIONIC|DEAQ]]                | 18+      |
| ... did you cry a lot?                                                                                                                                                                                                                                       | ...huilde u veel?                                                                                                                                                                                                                                               | lidas_mdd_adu_q_16     | depsymp15     | [[BIONIC|DEAQ]]                | 18+      |
| ... did you often feel helpless?                                                                                                                                                                                                                             | ...voelde u zich vaak hulpeloos?                                                                                                                                                                                                                                | lidas_mdd_adu_q_17     | depsymp16     | [[BIONIC|DEAQ]]                | 18+      |
| ... did you often feel nervous, agitated or anxious?                                                                                                                                                                                                         | ...voelde u zich vaak zenuwachtig, gejaagd of angstig?                                                                                                                                                                                                          | lidas_mdd_adu_q_18     | depsymp17     | [[BIONIC|DEAQ]]                | 18+      |
| ... did you suffer from trembling or shaking?                                                                                                                                                                                                                | ...had u last van trillen of beven?                                                                                                                                                                                                                             | lidas_mdd_adu_q_19     | depsymp18     | [[BIONIC|DEAQ]]                | 18+      |
| ... did you experience shortness of breath or did you have trouble breathing?                                                                                                                                                                                | ...was u kortademig of had u moeite met ademhalen?                                                                                                                                                                                                              | lidas_mdd_adu_q_20     | depsymp19     | [[BIONIC|DEAQ]]                | 18+      |
| ... did you have a pounding or fluttering heart or heart palpitations?                                                                                                                                                                                       | ...had u een bonzend of overslaand hart of hartkloppingen?                                                                                                                                                                                                      | lidas_mdd_adu_q_21     | depsymp20     | [[BIONIC|DEAQ]]                | 18+      |
| ... did you have a sense of unreality, like an out-of-body experience?                                                                                                                                                                                       | ...had u een gevoel van onwerkelijkheid, alsof u los van uzelf stond?                                                                                                                                                                                           | lidas_mdd_adu_q_22     | depsymp21     | [[BIONIC|DEAQ]]                | 18+      |
| ... did you feel dizzy, unsteady, lightheaded, as if you were about to faint?                                                                                                                                                                                | ...voelde u zich duizelig, onvast, licht in het hoofd, alsof u zou flauwvallen?                                                                                                                                                                                 | lidas_mdd_adu_q_23     | depsymp22     | [[BIONIC|DEAQ]]                | 18+      |
| during such a period, did you experience attacks more than once, in which you suddenly felt anxious, startled, uncomfortable, in situations in which most people wouldn't feel that way?                                                                     | Tijdens deze periode, hebt u meer dan eens aanvallen meegemaakt waarbij u zich plotseling heel angstig, geschrokken, onbehaaglijk of gespannen voelde, en dat in situaties waarin de meeste mensen dat niet zouden zijn?                                        | lidas_mdd_adu_q_24     | depsymp23     | [[BIONIC|DEAQ]]                | 18+      |
| did such an attack reach a peak within 10 minutes? / during such a period, did you experience attacks more than once, in which you suddenly felt anxious, startled, uncomfortable, in situations in which most people wouldn't feel that way?                | Bereikte zo'n aanval een piek binnen 10 minuten?                                                                                                                                                                                                                | lidas_mdd_adu_q_24_a   | depsymp24     | [[BIONIC|DEAQ]]                | 18+      |
| did any of these periods lasting two weeks or longer seriously interfere with your ability to do your job, take care of your house or family, or take care of yourself?                                                                                      | belemmerde een van deze periodes van twee weken of langer u ernstig in uw functioneren op uw werk, of in het zorgen voor het huishouden, uw familie of uzelf?                                                                                                   | lidas_mdd_adu_q_25     | depfunct5     | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| how long did the longest of periods like this last? you may give an estimate                                                                                                                                                                                 | hoe lang duurde de langste van dergelijke periodes? u mag een schatting geven                                                                                                                                                                                   | lidas_mdd_adu_q_26     | deptime1      | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| how many periods like this did you have in your lifetime?                                                                                                                                                                                                    | hoeveel van dergelijke periodes hebt u in uw leven gehad?                                                                                                                                                                                                       | lidas_mdd_adu_q_27     | deptime2      | [[BIONIC|DEPQ+DEAQ]]           | 18+      |
| how many periods like this did you have in your lifetime?                                                                                                                                                                                                    | hoeveel van dergelijke periodes hebt u in uw leven gehad?                                                                                                                                                                                                       | lidas_mdd_adu_q_27_v2  | deptime2__1   | [[MHDQ]]                       | 18+      |
| did you have a period like this in the last 12 months?                                                                                                                                                                                                       | hebt u een dergelijke periode in de afgelopen 12 maanden gehad?                                                                                                                                                                                                 | lidas_mdd_adu_q_28     | deptime3      | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| how old were you the first time you had a period like this? (whether or not you received any help for it)                                                                                                                                                    | hoe oud was u de eerste keer dat u zo'n periode meemaakte? (ongeacht of u hiervoor hulp hebt gekregen)                                                                                                                                                          | lidas_mdd_adu_q_29     | deptime4      | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| was this period of at least two weeks in which you felt sad, empty, or depressed or you lost your interest in things caused by negative events or was there no reason for it?                                                                                | Werd deze periode, van tenminste twee weken waarin u zich somber, leeg of depressief voelde of uw interesse voor dingen verloor, veroorzaakt door nare gebeurtenissen of was er geen reden voor?                                                                | lidas_mdd_adu_q_30     | depsymp25     | [[BIONIC|DEAQ]]                | 18+      |


===Mania===
| **Label English**                                                                                                                                                                          | **Label Dutch**                                                                                                                                                                                                    | **Code**                | **Variable**  | **Assessment**   | **Age**  |
| was there ever a period in which you felt excessively elated, irritable or so full of energy and self-assured that it got you into trouble or other people thought you were not yourself?  | hebt u zich ooit een periode bijzonder uitgelaten, prikkelbaar of zo boordevol energie en zelfverzekerd gevoeld dat u daardoor in moeilijkheden bent geraakt of dat anderen dachten dat u uit uw gewone doen was?  | lidas_mania_adu_q_01    | depsymp26     | [[BIONIC|DEAQ]]  | 18+      |
| did this period (in which you felt excessively elated, irritable, or full of energy and self-assured) last for four or more consecutive days?                                              | duurde deze periode (dat u zich bijzonder uitgelaten, prikkelbaar of zo boordevol energie en zelfverzekerd voelde) vier aaneengesloten dagen of langer?                                                            | lidas_mania_adu_q_01_a  | depsymp27     | [[BIONIC|DEAQ]]  | 18+      |

===General anxiety disorder===
| **Label English**                                                                                                                                                                               | **Label Dutch**                                                                                                                                                                                      | **Code**              | **Variable**  | **Assessment**   | **Age**  |
| have you ever had a period in which you were excessively anxious or worried about multiple problems in daily life, at work, at home or in your immediate environment?                               | hebt u ooit een periode gehad dat u overmatig angstig was of veel piekerde en zich zorgen maakte over meerdere problemen van het dagelijks leven, op het werk, thuis of in uw naaste omgeving?           | lidas_gad_adu_q_01    | depsymp28     | [[BIONIC|DEAQ]]  | 18+      |
| was this anxiety or worry present nearly every day?                                                                                                                                                 | was deze angst of bezorgdheid bijna elke dag aanwezig?                                                                                                                                                   | lidas_gad_adu_q_01_a  | depsymp29     | [[BIONIC|DEAQ]]  | 18+      |
| did you have difficulties controlling this anxiety or worry or did it affect your ability to concentrate?                                                                                           | vond u het moeilijk om deze angst of bezorgdheid in de hand te houden of belemmerde dit u om zich te concentreren?                                                                                       | lidas_gad_adu_q_01_b  | depsymp30     | [[BIONIC|DEAQ]]  | 18+      |
| have you ever felt excessively anxious or worried for a period of at least 6 months?                                                                                                                | hebt u zich ooit wel eens gedurende een periode van tenminste 6 maanden overmatig angstig of bezorgd gevoeld?                                                                                            | lidas_gad_adu_q_01_c  | depsymp31     | [[BIONIC|DEAQ]]  | 18+      |
| In the worst period of at least 6 months in which you felt excessively anxious or worried:                                                                                                          | In de ergste periode van tenminste 6 maanden waarin u zich overmatig angstig of bezorgd voelde                                                                                                           |                       |               | [[BIONIC|DEAQ]]  | 18+      |
| ... did you feel restless, charged, or nervous most of the time?                                                                                                                                    | ... voelde u zich toen meestal rusteloos, geladen of zenuwachtig?                                                                                                                                        | lidas_gad_adu_q_02_a  | depsymp32     | [[BIONIC|DEAQ]]  | 18+      |
| ... did you feel tense most of the time?                                                                                                                                                            | ... voelde u zich toen meestal gespannen?                                                                                                                                                                | lidas_gad_adu_q_02_b  | depsymp33     | [[BIONIC|DEAQ]]  | 18+      |
| ... did you feel tired, weak, or easily exhausted most of the time?                                                                                                                                 | ... voelde u zich toen meestal vermoeid, zwak of snel uitgeput?                                                                                                                                          | lidas_gad_adu_q_02_c  | depsymp34     | [[BIONIC|DEAQ]]  | 18+      |
| ... did you have difficulties concentrating most of the time, or did you have 'black-outs'?                                                                                                         | ... kon u zich toen meestal moeilijk concentreren of had u dat u ineens 'niets meer wist'?                                                                                                               | lidas_gad_adu_q_02_d  | depsymp35     | [[BIONIC|DEAQ]]  | 18+      |
| ... were you excessively irritable most of the time?                                                                                                                                                | ... was u toen meestal bijzonder prikkelbaar?                                                                                                                                                            | lidas_gad_adu_q_02_e  | depsymp36     | [[BIONIC|DEAQ]]  | 18+      |
| ... did you have sleeping problems most of the time?                                                                                                                                                | ... had u toen meestal slaapproblemen?                                                                                                                                                                   | lidas_gad_adu_q_02_f  | depsymp37     | [[BIONIC|DEAQ]]  | 18+      |
| did this period of at least 6 months (in which you felt excessively anxious or worried) serioulsy impair your ability to function at work or to care for your household, your family, or yourself?  | belemmerde deze periode van 6 maanden of langer (waarin u zich overmatig angstig of bezorgd voelde) u ernstig in uw functioneren op uw werk, of in het zorgen voor het huishouden, uw familie of uzelf?  | lidas_gad_adu_q_03    | depsymp38     | [[BIONIC|DEAQ]]  | 18+      |
| was this anxious or worried period caused by negative events or was there no reason for it?                                                                                                         | werd deze angstige of bezorgde periode veroorzaakt door nare gebeurtenissen of was er geen reden voor?                                                                                                   | lidas_gad_adu_q_04    | depsymp40     | [[BIONIC|DEAQ]]  | 18+      |
| how long did the longest period of anxiety or worry last?                                                                                                                                           | hoe lang duurde de langste angstige of bezorgde periode?                                                                                                                                                 | lidas_gad_adu_q_05_a  | depsymp39     | [[BIONIC|DEAQ]]  | 18+      |
| how many anxious or worried periods did you experience in your lifetime?                                                                                                                            | hoeveel angstige of bezorgde periodes hebt u in uw leven gehad?                                                                                                                                          | lidas_gad_adu_q_05_b  | deptime5      | [[BIONIC|DEAQ]]  | 18+      |
| have you had an anxious or worried period like this in the past 12 months?                                                                                                                          | hebt u een dergelijke angstige of bezorgde periode in de afgelopen 12 maanden gehad?                                                                                                                     | lidas_gad_adu_q_05_c  | deptime7      | [[BIONIC|DEAQ]]  | 18+      |
| how old were you when you first experienced such an anxious or worried period?                                                                                                                      | hoe oud was u de eerste keer dat u zo'n angstige of bezorgde periode meemaakte?                                                                                                                          | lidas_gad_adu_q_05_d  | deptime6      | [[BIONIC|DEAQ]]  | 18+      |

===Agoraphobia===
| **Label English**                                                                                                                                                                                       | **Label Dutch**                                                                                                                                                                                                               | **Code**               | **Variable**  | **Assessment**   | **Age**  |
| have you ever felt excessively anxious or uncomfortable in a place or situation from which it would be impossible or embarassing to escape, or where no help would be available in case of a panic attack?  | hebt u zich ooit bijzonder angstig of onbehaaglijk gevoeld op een plaats of in een situatie van waaruit ontsnappen moeilijk of gênant was, of waar geen hulp beschikbaar zou kunnen zijn wanneer u een paniekaanval zou krijgen?  | lidas_agph_adu_q_06_a  | depsymp41     | [[BIONIC|DEAQ]]  | 18+      |
| was your fear of those places or situations so serious that you avoided them, you had yourself be accompanied, or endured them with a lot of discomfort?                                                    | was uw angst voor die plaatsen of situaties zo erg dat u ze vermeed, zich liet begeleiden of ze met veel ongemak doorstond?                                                                                                       | lidas_agph_adu_q_06_b  | depsymp42     | [[BIONIC|DEAQ]]  | 18+      |

===Social phobia===
| **Label English**                                                                                                                                                                                                      | **Label Dutch**                                                                                                                                                                                                                                       | **Code**              | **Variable**  | **Assessment**   | **Age**  |
| have you ever had a fear of being the center of attention or were you afraid to be humiliated? for example when you had to speak in public, eat in company, write while being watched, or during other social activities?  | hebt u ooit angst gehad om in het middelpunt van de belangstelling te staan of vernederd te worden? bijv. wanneer u moest spreken voor een groep mensen, eten in gezelschap, schrijven terwijl anderen toekeken, of tijdens andere sociale activiteiten?  | lidas_sph_adu_q_07_a  | depsymp43     | [[BIONIC|DEAQ]]  | 18+      |
| did you consider this an excessive or unreasonable fear? / have you ever had a fear of being the center of attention or were you afraid to be humiliated?                                                                  | was deze angst overdreven of onredelijk volgens u? / hebt u ooit angst gehad om in het middelpunt van de belangstelling te staan of vernederd te worden?                                                                                                  | lidas_sph_adu_q_07_b  | depsymp44     | [[BIONIC|DEAQ]]  | 18+      |
| did you have such a fear for social activities that you avoided them, or endured them with a lot of effort?                                                                                                                | had u zulke angst voor die sociale activiteiten dat u ze in de praktijk vermeed, of ze met veel moeite doorstond?                                                                                                                                         | lidas_sph_adu_q_07_c  | depsymp45     | [[BIONIC|DEAQ]]  | 18+      |
| did this fear affect your normal work or social activities or was it the cause for serious discomfort?                                                                                                                     | verstoorde deze angst uw normale werkzaamheden, uw sociale activiteiten of was zij de oorzaak van ernstig ongemak?                                                                                                                                        | lidas_sph_adu_q_07_d  | depsymp46     | [[BIONIC|DEAQ]]  | 18+      |

===Diagnoses and treatment===
| **Label English**                                                                                                                                                                                                                                                                                                                                                                                                             | **Label Dutch**                                                                                                                                                                                                                                                                                                                                                                                                                                                                    | **Code**                      | **Variable**  | **Assessment**                 | **Age**  |
| have you ever had contact with a social service organization for problems that you had, that were not related  to your physical health? (for example a mental health institute, psychologist, or social work)?                                                                                                                                                                                                                | hebt u ooit contact gehad met hulpverleningsinstanties voor problemen van uzelf die niet te maken hadden met uw lichamelijke gezondheid? (bv. ggz, psycholoog of maatschappelijk werk)                                                                                                                                                                                                                                                                                             | lidas_diagnosis_adu_q_01      | other1        | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| please indicate with which disorders you ever have been diagnosed by a professional or medical doctor? None of these disorders / Depression / Bipolar disorder (manic depression) / Schizophrenia or psychosis / Eating disorder / Anxiety disorder / Panic disorder / Obsessive compulsive disorder / Posttraumatic stress disorder / Phobia / ADD-ADHD / Personality disorder / Alcohol addiction / Drug addiction / Other  | Wilt u van de volgende lijst aandoeningen aanvinken of deze ooit bij u zijn vastgesteld door een hulpverlener of arts? \\Geen van onderstaande aandoeningen / Depressie / Bipolaire stoornis (manisch depressief) / Schizofrenie of psychose / Eetstoornis / Angststoornis / Paniekstoornis / Obsessieve compulsieve stoornis (dwangstoornis) / Postraumatische stress stoornis / Fobie / ADD-ADHD / Persoonlijkheidsstoornis / Alcoholverslaving / Drugsverslaving / Anders, nl.  | lidas_diagnosis_adu_q_01_a-o  | other2a-o     | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| specification other disorder / please indicate with which disorders you ever have been diagnosed by a professional or medical doctor?                                                                                                                                                                                                                                                                                         | specificatie andere aandoening / wilt u van de onderstaande aandoeningen aanvinken of deze ooit bij u zijn vastgesteld door een hulpverlener of arts?                                                                                                                                                                                                                                                                                                                              | lidas_diagnosis_adu_q_01_o1   | other2o1      | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| did you ever tell a professional about these problems (for example a medical doctor, psychologist, social worker, nurse, or other helping professional)?                                                                                                                                                                                                                                                                      | hebt u ooit met een hulpverlener (bv. een arts, psycholoog, sociaal werker, verpleegkundige, of een andere professionele hulpverlener) gesproken over deze problemen?                                                                                                                                                                                                                                                                                                              | lidas_treatment_adu_q_01      | deptreat1     | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| have you ever been treated or monitored by a caregiver or doctor for the following disorders? None of these disorders / Depression / Bipolar disorder (manic depression) / Schizophrenia or psychosis / Eating disorder / Anxiety disorder / Panic disorder / Obsessive compulsive disorder / Posttraumatic stress disorder / Phobia / ADD-ADHD / Personality disorder / Alcohol addiction / Drug addiction / Other           | Bent u voor de volgende aandoeningen ooit onder behandeling of controle van een hulpverlener of arts geweest? Geen van onderstaande aandoeningen / Depressie / Bipolaire stoornis (manisch depressief) / Schizofrenie of psychose / Eetstoornis / Angststoornis / Paniekstoornis / Obsessieve compulsieve stoornis (dwangstoornis) / Postraumatische stress stoornis / Fobie / ADD-ADHD / Persoonlijkheidsstoornis / Alcoholverslaving / Drugsverslaving / Anders, nl.             | lidas_treatment_adu_q_02_a-o  | other3a-o     | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| specification other disorder / have you ever been treated or monitored by a caregiver or doctor for the following disorders?                                                                                                                                                                                                                                                                                                  | specificatie andere aandoening / bent u voor de volgende aandoeningen ooit onder behandeling of controle van een hulpverlener of arts geweest?                                                                                                                                                                                                                                                                                                                                     | lidas_treatment_adu_q_02_o1   | other3o1      | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| have you ever had the following treatments? None of these treatments / Antidepressants / Psychotherapy / Online support programme or e-health intervention / Running therapy or physical exercise / Light therapy /Hospitalization in a mental health unit / Electroconvulsive therapy (ect) / Other                                                                                                                          | Heeft u ooit de volgende behandelingen gehad? \\ Geen van onderstaande behandelingen / antidepressiva / psychotherapie / online hulpprogramma of e-health interventie / running therapy of fysieke inspanning / lichttherapie / opname in psychiatrisch ziekenhuis / ECT / anders                                                                                                                                                                                                  | lidas_treatment_adu_q_03_a-i  | treat1a-i     | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |
| specification other treatment / have you ever had the following treatments?                                                                                                                                                                                                                                                                                                                                                   | specificatie andere behandeling / hebt u ooit de volgende behandelingen gehad?                                                                                                                                                                                                                                                                                                                                                                                                     | lidas_treatment_adu_q_03_i1   | treat1i1      | [[BIONIC|DEPQ+DEAQ]] [[MHDQ]]  | 18+      |

===Family depression and anxiety===
| **Label English**                                                                                              | **Label Dutch**                                                                                | **Code**               | **Variable**  | **Assessment**   | **Age**  |
| do you think that your biological father has had problems with depression or anxiety?                              | denkt u dat uw biologische vader problemen heeft gehad met depressie of angst?                     | lidas_depanx_fam_q_01  | depfam1       | [[BIONIC|DEAQ]]  | 18+      |
| do you think that your biological mother has had problems with depression or anxiety?                              | denkt u dat uw biologische moeder problemen heeft gehad met depressie of angst?                    | lidas_depanx_fam_q_02  | depfam2       | [[BIONIC|DEAQ]]  | 18+      |
| do you think that one of your biological siblings has had problems with depression or anxiety?                     | denkt u dat een van uw biologische broers of zussen problemen heeft gehad met depressie of angst?  | lidas_depanx_fam_q_03  | depfam3       | [[BIONIC|DEAQ]]  | 18+      |
| do you think that one of your uncles/aunts/grandfathers/grandmothers has had problems with depression or anxiety?  | denkt u dat een van uw ooms/tantes/opa's/oma's problemen heeft gehad met depressie of angst?       | lidas_depanx_fam_q_04  | depfam4       | [[BIONIC|DEAQ]]  | 18+      |
| do you think that one of your biological children has had problems with depression or anxiety?                     | denkt u dat een van uw biologische kinderen problemen heeft gehad met depressie of angst?          | lidas_depanx_fam_q_05  | depfam5       | [[BIONIC|DEAQ]]  | 18+      |