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| __Responsiveness__ of the instrument has been assessed by measuring decline in cognitive performance of patients with mild Alzheimer’s Disease on the International Shopping List Test (ISLT); a subtest of the Cogstate((Lim, Y. Y., Pietrzak, R. H., Snyder, P. J., Darby, D., & Maruff, P. (2012). Preliminary data on the effect of culture on the assessment of alzheimer's disease-related verbal memory impairment with the international shopping list test. Archives of Clinical Neuropsychology : The Official Journal of the National Academy of Neuropsychologists, 27(2), 136-147)). Results show that compared to controls, patients with Alzheimer’s Disease show deterioration in verbal memory over a period of one year. We would expect similar results on all other subtests of the CogState suggesting that the Cogstate is sensitive to changes in cognitive functioning in persons with Alzheimer’s disease. A longer period of follow-up would be needed to be able to say something about responsiveness among the general population (i.e. persons without cognitive impairments). | __Responsiveness__ of the instrument has been assessed by measuring decline in cognitive performance of patients with mild Alzheimer’s Disease on the International Shopping List Test (ISLT); a subtest of the Cogstate((Lim, Y. Y., Pietrzak, R. H., Snyder, P. J., Darby, D., & Maruff, P. (2012). Preliminary data on the effect of culture on the assessment of alzheimer's disease-related verbal memory impairment with the international shopping list test. Archives of Clinical Neuropsychology : The Official Journal of the National Academy of Neuropsychologists, 27(2), 136-147)). Results show that compared to controls, patients with Alzheimer’s Disease show deterioration in verbal memory over a period of one year. We would expect similar results on all other subtests of the CogState suggesting that the Cogstate is sensitive to changes in cognitive functioning in persons with Alzheimer’s disease. A longer period of follow-up would be needed to be able to say something about responsiveness among the general population (i.e. persons without cognitive impairments). |
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| __Cogstate in Lifelines__: correlations between the Cogstate and [[Ruff Figural Fluency Test|RFFT]] scores are described in a paper by Kuiper et al. ((Kuiper, J.S., Oude Voshaar, R.C., Verhoeven, F.E.A., Zuidema, S.U., and Smidt, N. (2017). Comparison of cognitive functioning as measured by the Ruff Figural Fluency Test and the Cogstate computerized battery within the LifeLines Cohort Study. BMC Psychol. 5, 15)) | __Cogstate in Lifelines__: |
| | For some variables, Lifelines used the outcome metrics defined by Cogstate. Specifically, reaction-time measures were summarized as the mean log10 reaction time for correct trials, and accuracy measures as arcsine(√proportion-correct). These transformations are specified on the Cogstate test pages and are standard in Cogstate datasets to address distributional properties typical of cognitive data and to support comparability across studies. |
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| | Correlations between the Cogstate and [[Ruff Figural Fluency Test|RFFT]] scores are described in a paper by Kuiper et al. ((Kuiper, J.S., Oude Voshaar, R.C., Verhoeven, F.E.A., Zuidema, S.U., and Smidt, N. (2017). Comparison of cognitive functioning as measured by the Ruff Figural Fluency Test and the Cogstate computerized battery within the LifeLines Cohort Study. BMC Psychol. 5, 15)) |
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| | **Task in order of completion**| **Suffix** | | | **Task in order of completion** | **Suffix** | |
| | Detection task | _01 | | | Detection task | _02 | |
| | Identification task | _02 | | | Identification task | _01 | |
| | One back task | _04 | | | One back task | _04 | |
| | One Card Learning task | _03 | | | One Card Learning task | _03 | |
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| | === Completion criteria 2A === |
| | the Cogstate variables are, just as all other data, presented 'as-is'. Meaning that all available data will be present. The Cogstate research group has a completion criteria for all participants. This criteria determines when according to their standards the test was valid. If a participant scored too low on one of the following variables the results of the test is considered invalid. |
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| | | **Task in order of completion** | **cogstate_stimuli_all_m_1** | **cogstate_hitrate_all_m_1** | |
| | | Detection task | < 27 | < 80% | |
| | | Identification task | < 23 | < 80% | |
| | | One back task | < 24 | < 70% | |
| | | One Card Learning task | < 60 | < 50% | |
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| | **Label English** | **Code** | **Variable** | **Assessment** | **Age** | | | **Label English** | **Code** | **Variable** | **Assessment** | **Age** | |
| | Session passed completion criteria? | cogstate_completion_all_m_2 | SessionCompletionPass | [[3A Visit 1]] | 13+ | | | Session passed completion criteria? | cogstate_completion_all_m_2 | SessionCompletionPass | [[3A Visit 1]] | 13+ | |
| | | Test completion criteria | cogstate_completion_all_m_1_XX | COMPLETION | [[3A Visit 1]] | 13+ | |
| | Test performance criteria | cogstate_completion_all_m_2_XX | TestCompletionPass | [[3A Visit 1]] | 13+ | | | Test performance criteria | cogstate_completion_all_m_2_XX | TestCompletionPass | [[3A Visit 1]] | 13+ | |
| | Session passed performance criteria? | cogstate_performance_all_m_2 | SessionPerformancePass | [[3A Visit 1]] | 13+ | | | Session passed performance criteria? | cogstate_performance_all_m_2 | SessionPerformancePass | [[3A Visit 1]] | 13+ | |
| | Test performance criteria | cogstate_performance_all_m_2_XX | TestPerformancePass | [[3A Visit 1]] | 13+ | | | Test performance criteria | cogstate_performance_all_m_2_XX | TestPerformancePass | [[3A Visit 1]] | 13+ | |
| | | Test integrity criteria | cogstate_integrity_all_m_1_XX | INTEGRITY | [[3A Visit 1]] | 13+ | |
| | Session passed integrity criteria? | cogstate_integrity_all_m_2 | SessionIntegrityPass | [[3A Visit 1]] | 13+ | | | Session passed integrity criteria? | cogstate_integrity_all_m_2 | SessionIntegrityPass | [[3A Visit 1]] | 13+ | |
| | Test integrity criteria <sup> i </sup> | cogstate_integrity_all_m_2_XX | TestIntegrityPass | [[3A Visit 1]] | 13+ | | | Test integrity criteria <sup> i </sup> | cogstate_integrity_all_m_2_XX | TestIntegrityPass | [[3A Visit 1]] | 13+ | |
| | The score on the primary outcome for this test <sup> ii </sup> | cogstate_primaryoutcome_all_m_2_XX | PrimaryOutcome | [[3A Visit 1]] | 13+ | | | The score on the primary outcome for this test <sup> ii </sup> | cogstate_primaryoutcome_all_m_2_XX | PrimaryOutcome | [[3A Visit 1]] | 13+ | |
| | The score on the alternate outcome for this test <sup> iii </sup> | cogstate_outcomealt_all_m_2_XX | AlternateOutcome | [[3A Visit 1]] | 13+ | | | The score on the alternate outcome for this test <sup> iii </sup> | cogstate_outcomealt_all_m_2_XX | AlternateOutcome | [[3A Visit 1]] | 13+ | |
| | | Speed measure - mean of reaction time for correct responses | cogstate_speed_all_m_1_XX | LMNUNTRANS | [[2A Visit 1]] \\ [[3A Visit 1]] | 13+ | |
| | | Speed measure - standard deviation of the log10 transformed reaction time for correct responses | cogstate_logstdev_all_m_1_XX | LSD | [[2A Visit 1]] \\ [[3A Visit 1]] | 13+ | |
| | Raw reaction time of performance (ms) | cogstate_speed_all_m_2_XX | RawReactionTime | [[3A Visit 1]] | 13+ | | | Raw reaction time of performance (ms) | cogstate_speed_all_m_2_XX | RawReactionTime | [[3A Visit 1]] | 13+ | |
| | | Speed measure - mean of the log10 transformed reaction time for correct responses | cogstate_speedtransf_all_m_1_XX | LMNTRANS | [[2A Visit 1]] \\ [[3A Visit 1]] | 13+ | |
| | Reaction time of performance (log10 ms) | cogstate_speedtransf_all_m_2_XX | ReactionTime | [[3A Visit 1]] | 13+ | | | Reaction time of performance (log10 ms) | cogstate_speedtransf_all_m_2_XX | ReactionTime | [[3A Visit 1]] | 13+ | |
| | Raw consistency of performance (ms) | cogstate_consistency_m_2_XX | RawRTVariability | [[3A Visit 1]] | 13+ | | | Raw consistency of performance (ms) | cogstate_consistency_m_2_XX | RawRTVariability | [[3A Visit 1]] | 13+ | |
| | Consistency of performance (log10 ms) | cogstate_consistencytransf_m_2_XX | RTVariability | [[3A Visit 1]] | 13+ | | | Consistency of performance (log10 ms) | cogstate_consistencytransf_m_2_XX | RTVariability | [[3A Visit 1]] | 13+ | |
| | Raw accuracy of performance | cogstate_accuracy_all_m_2_XX | RawAccuracy | [[3A Visit 1]] | 13+ | | | Raw accuracy of performance | cogstate_accuracy_all_m_2_XX | RawAccuracy | [[3A Visit 1]] | 13+ | |
| | | Accuracy measure - arcsine square root transformed - hitrate (correct responses divided by total responses (total includes TPos, TNeg, FPos, FNeg, anticipations and max outs) | cogstate_hitratetransf_all_m_1_XX | ACCTRANS | [[2A Visit 1]] \\ [[3A Visit 1]] | 13+ | |
| | | Accuracy measure - hit rate (correct responses divided by total responses (total includes TPos, TNeg, FPos, FNeg, anticipations and max outs) | cogstate_hitrate_all_m_1_XX | ACCUNTRANS | [[2A Visit 1]] \\ [[3A Visit 1]] | 13+ | |
| | Accuracy of performance (arcsine square root proportion correct) | cogstate_accuracytransf_all_m_2_XX | Accuracy | [[3A Visit 1]] | 13+ | | | Accuracy of performance (arcsine square root proportion correct) | cogstate_accuracytransf_all_m_2_XX | Accuracy | [[3A Visit 1]] | 13+ | |
| | Number of correct responses / test XX | cogstate_correct_all_m_2_XX | TotalCorrect | [[3A Visit 1]] | 13+ | | | Total presentations or trials. | cogstate_presentations_all_m_1_XX | PRESNT | [[2A Visit 1]] \\ [[3A Visit 1]] | 13+ | |
| | | Total correct responses | cogstate_correct_all_m_1_XX | COR | [[2A Visit 1]] \\ [[3A Visit 1]] | 13+ | |
| | | Number of correct responses | cogstate_correct_all_m_2_XX | TotalCorrect | [[3A Visit 1]] | 13+ | |
| | Number of correct responses after pant responses have been excluded | cogstate_correctexclpant_all_m_2_XX | TotalCorrectExclPant | [[3A Visit 1]] | 13+ | | | Number of correct responses after pant responses have been excluded | cogstate_correctexclpant_all_m_2_XX | TotalCorrectExclPant | [[3A Visit 1]] | 13+ | |
| | | Total error responses (includes FPos, FNeg, anticipations and max outs). | cogstate_errors_all_m_1_XX | ERR | [[2A Visit 1]] \\ [[3A Visit 1]] | 13+ | |
| | Number of errors | cogstate_errors_all_m_2_XX | TotalErrors | [[3A Visit 1]] | 13+ | | | Number of errors | cogstate_errors_all_m_2_XX | TotalErrors | [[3A Visit 1]] | 13+ | |
| | Number of legal errors | cogstate_legalerrors_all_m_2_XX | LegalErrors | [[3A Visit 1]] | 13+ | | | Number of legal errors | cogstate_legalerrors_all_m_2_XX | LegalErrors | [[3A Visit 1]] | 13+ | |
| | Number of maxout responses <sup> iv </sup> | cogstate_maxout_all_m_2_XX | TotalMaxOut | [[3A Visit 1]] | 13+ | | | Number of maxout responses <sup> iv </sup> | cogstate_maxout_all_m_2_XX | TotalMaxOut | [[3A Visit 1]] | 13+ | |
| | number of responses (correct + errors) | cogstate_responses_all_m_2_XX | TotalResponses | [[3A Visit 1]] | 13+ | | | number of responses (correct + errors) | cogstate_responses_all_m_2_XX | TotalResponses | [[3A Visit 1]] | 13+ | |
| | | CPAL and ISLT specific - "Stimuli". For CPAL is total filled markers, and for ISLT is total words in the presented list. | cogstate_stimuli_all_m_1_XX | STI | [[2A Visit 1]] \\ [[3A Visit 1]] | 13+ | |
| | Number of stimuli | cogstate_stimuli_all_m_2_XX | TotalTrials | [[3A Visit 1]] | 13+ | | | Number of stimuli | cogstate_stimuli_all_m_2_XX | TotalTrials | [[3A Visit 1]] | 13+ | |
| | Standardized z-score for the primary outcome measure | cogstate_zscore_all_m_2_XX | StandardScoreZ | [[3A Visit 1]] | 13+ | | | Standardized z-score for the primary outcome measure | cogstate_zscore_all_m_2_XX | StandardScoreZ | [[3A Visit 1]] | 13+ | |
| | The score on the learning/working memory composite, incorporating the primary outcome measures for the one card learning and one back tests (accuracy), relative to age-matched normative data | cogstate_learnwmscore_all_m_2_XX | LearnWMStdScr | [[3A Visit 1]] | 13+ | | | The score on the learning/working memory composite, incorporating the primary outcome measures for the one card learning and one back tests (accuracy), relative to age-matched normative data | cogstate_learnwmscore_all_m_2_XX | LearnWMStdScr | [[3A Visit 1]] | 13+ | |
| | The score on the learning/working memory composite, incorporating the primary outcome measure for the ocl test (accuracy) and the alternate outcome measure for the onb test (reaction time), relative to age-matched normative data | cogstate_scorealt_all_m_2_XX | AltLearnWMStdScr | [[3A Visit 1]] | 13+ | | | The score on the learning/working memory composite, incorporating the primary outcome measure for the ocl test (accuracy) and the alternate outcome measure for the onb test (reaction time), relative to age-matched normative data | cogstate_scorealt_all_m_2_XX | AltLearnWMStdScr | [[3A Visit 1]] | 13+ | |
| | Left- or righthanded | cogstate_handedness_all_q_1 | Hand | [[3A Visit 1]] | 13+ | | | Left- or righthanded | cogstate_handedness_all_q_1 | HAND | [[3A Visit 1]] | 13+ | |
| | Test completion criteria | cogstate_completion_all_m_1_XX | Completion | [[3A Visit 1]] | 13+ | | |
| | Test integrity criteria | cogstate_integrity_all_m_1_XX | Integrity | [[3A Visit 1]] | 13+ | | |
| | Total presentations or trials. | cogstate_presentations_all_m_1_XX | PRESNT | [[2A Visit 1]] \\ [[3A Visit 1]] | 13+ | | |
| | Total correct responses | cogstate_correct_all_m_1_XX | COR | [[2A Visit 1]] \\ [[3A Visit 1]] | 13+ | | |
| | Total error responses (includes FPos, FNeg, anticipations and max outs). | cogstate_errors_all_m_1_XX | ERR | [[2A Visit 1]] \\ [[3A Visit 1]] | 13+ | | |
| | Speed measure - mean of the log10 transformed reaction time for correct responses | cogstate_speedtransf_all_m_1_XX | LMNTRANS | [[2A Visit 1]] \\ [[3A Visit 1]] | 13+ | | |
| | Speed measure - mean of reaction time for correct responses | cogstate_speed_all_m_1_XX | LMNUNTRANS | [[2A Visit 1]] \\ [[3A Visit 1]] | 13+ | | |
| | Speed measure - standard deviation of the log10 transformed reaction time for correct responses | cogstate_logstdev_all_m_1_XX | LSD | [[2A Visit 1]] \\ [[3A Visit 1]] | 13+ | | |
| | Accuracy measure - arcsine square root transformed - hitrate (correct responses divided by total responses (total includes TPos, TNeg, FPos, FNeg, anticipations and max outs) | cogstate_hitratetransf_all_m_1_XX | ACCTRANS | [[2A Visit 1]] \\ [[3A Visit 1]] | 13+ | | |
| | Accuracy measure - hit rate (correct responses divided by total responses (total includes TPos, TNeg, FPos, FNeg, anticipations and max outs) | cogstate_hitrate_all_m_1_XX | ACCUNTRANS | [[2A Visit 1]] \\ [[3A Visit 1]] | 13+ | | |
| | CPAL and ISLT specific - "Stimuli". For CPAL is total filled markers, and for ISLT is total words in the presented list. | cogstate_stimuli_all_m_1_XX | STI | [[2A Visit 1]] \\ [[3A Visit 1]] | 13+ | | |
| <sup> i </sup> Only calculated on test _02 (Identification task) \\ | <sup> i </sup> Only calculated on test _02 (Identification task) \\ |
| <sup> ii </sup> Primary outcome is reaction time (Detection/Identification task) or accuracy (One Back/One Card Learning task) \\ | <sup> ii </sup> Primary outcome is reaction time (Detection/Identification task) or accuracy (One Back/One Card Learning task) \\ |
