bioq
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| - | ====== BIONIC (BIOQ) ====== | ||
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| - | BIONIC is the name of an [[additional assessments|additional assessment]] in Lifelines.\\ It was performed in collaboration with the Dutch BIONIC consortium and with the [[https://www.umcg.nl/EN/corporate/Departments/UCP/Research/Paginas/default.aspx|University Center of Psychiatry in Groningen]].\\ | ||
| - | The goal of BIOQ was to assess **lifetime** depression (in [[DEPQ]] and [[DEAQ]]) & generalized anxiety disorder (in [[DEAQ]]) in Lifelines participants by implementation of the [[Depression (LIDAS)|Lifetime Depression Assessment Self-Report]] (LIDAS) digital questionnaire plus some additional questions.\\ Note that **current** depression & anxiety of Lifelines participants were assessed in general assessments [[1A]], [[2A]] and [[3A]] using the [[MINI Neuropsychiatric Interview]]. | ||
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| - | ===== Subcohort ===== | ||
| - | BIOQ was executed in two time periods: in 2016 and 2018.\\ | ||
| - | * For [[DEPQ]] (2016), the [[Depression (LIDAS)|LIDAS]] was sent to all adult participants with a known e-mail address in the [[GWAS]] subcohort (n=~10.000). ~5500 participants (50%) filled in the questionnaire. ((Bot et al., Validity of LIDAS (LIfetime Depression Assessment Self-report): a self-report online assessment of lifetime major depressive disorder. Psychol Med. 2017 Jan;47(2):279-289)) ((Fedko et al., Measurement and genetic architecture of lifetime depression in the Netherlands as assessed by LIDAS (Lifetime Depression Assessment Self-report). Psychol Med. 2022 Feb;51(8):1-10))\\ | ||
| - | * For [[DEAQ]] (2018) (in collaboration with the [[https://www.umcg.nl/EN/corporate/Departments/UCP/Paginas/default.aspx|University Center of Psychiatry]] at the UMCG), the [[Depression (LIDAS)|LIDAS]] plus some additional questions was sent to all adult participants with a known e-mail address in the entire [[cohort]] (n=133.000). ~43.500 participants (36%) filled in the questionnaire. ((van Loo et al., The structure of the symptoms of major depression: Factor analysis of a lifetime worst episode of depressive symptoms in a large general population sample. J Affect Disord 307: 115-124)) | ||
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| - | ===== Variables ===== | ||
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| - | The BIOQ variables can be found on the [[DEPQ]] and [[DEAQ]] pages. | ||
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| - | ==== Funding==== | ||
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| - | This project was funded by the Dutch research infrastructure for biobanking (BBMRI-NL) as Rainbow project Phenomics 2.0 – proof of principle for major depressive disorder (RP-12). | ||
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bioq.1675263243.txt.gz · Last modified: 2025/02/05 14:49 (external edit)
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