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spirometry_validation [2021/05/06 17:22] laura [Spirometry validation and reference values] |
spirometry_validation [2021/05/06 17:51] laura [Reference values] |
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====== Spirometry validation and reference values ====== | ====== Spirometry validation and reference values ====== | ||
- | Researchers from the [[https://www.rug.nl/staff/j.m.vonk/|University Medical Center Groningen]] performed a validation of the [[Pulmonary Function Test]] from participants at [[1a_visit_1|1A visit 1]] and [[2a_visit_1|2A visit 1]] ([[sections]]: [[physical state]] ([[Pulmonary Function Test]]) and [[secondary & linked variables]]).\\ | + | Researchers from the [[https://www.rug.nl/staff/j.m.vonk/|University Medical Center Groningen]] performed a validation of the [[Pulmonary Function Test]] from participants at [[1a_visit_1|1A visit 1]] and [[2a_visit_1|2A visit 1]]. Additionally, reference values have been developed. ([[sections]]: [[physical state]] ([[Pulmonary Function Test]]) and [[secondary & linked variables]]).\\ |
The spirometry variables can be requested in the Lifelines catalogue or by mail (data@lifelines.nl).\\ | The spirometry variables can be requested in the Lifelines catalogue or by mail (data@lifelines.nl).\\ | ||
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* Test performed according to ATS criteria or | * Test performed according to ATS criteria or | ||
* Test not performed according to ATS criteria, but clinically reliable. | * Test not performed according to ATS criteria, but clinically reliable. | ||
- | In case both the pulmonologist and the Lifelines assistant judged the technical correctness, the priority is given to the judgment of the pulmonologist. | + | In case both the pulmonologist and the Lifelines assistant judged the technical correctness, the priority is given to the judgment of the pulmonologist.\\ |
+ | **Important:** part of the spirometry results have been listed as technically invalid, as a result the researchers from the UMCG recommend you to __NOT__ use these results in analyses.\\ | ||
+ | \\ | ||
=== Validation rules === | === Validation rules === | ||
To select only technically valid measurements the following rules were applied: | To select only technically valid measurements the following rules were applied: | ||
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=== Remarks UMCG researcher === | === Remarks UMCG researcher === | ||
* It is important to note that ethnicity has not been taken into account. Everyone has been treated as Caucasian. | * It is important to note that ethnicity has not been taken into account. Everyone has been treated as Caucasian. | ||
- | * There are a few adults subjects with a huge difference in height between [[1a_visit_1|1A visit 1]] and [[2a_visit_1|2A visit 1]] resulting in a huge difference in reference values. It is recommended to exclude the adult subjects with a height difference of more than 5 cm using the height variable. | + | * There are a few adults subjects with a huge difference in height between [[1a_visit_1|1A visit 1]] and [[2a_visit_1|2A visit 1]] resulting in a huge difference in reference values. It is recommended to exclude the adult subjects with a height difference of more than 5 cm using the height variable.\\ |
- | + | \\ | |
- | + | \\ | |
+ | ===== Article ===== | ||
+ | * Mahon, G. M., Koppelman, G. H., & Vonk, J. M. (2021). Grandmaternal smoking, asthma and lung function in the offspring: the Lifelines cohort study. Thorax, 76(5), 441-447. DOI: 10.1136/thoraxjnl-2020-215232\\ | ||
+ | \\ | ||
+ | \\ | ||
===== Variables ===== | ===== Variables ===== | ||
| **Label English** | **Label Dutch** | **Code** | **Variable** | **Assessment** | **Age** | | | **Label English** | **Label Dutch** | **Code** | **Variable** | **Assessment** | **Age** | | ||
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| FEF75 % predicted | FEF75 % voorspeld | fef75_percpredicted_all_c_1 | fef75pp | [[1A visit 1|1A]] [[2A visit 1|2A]] | 18+ | | | FEF75 % predicted | FEF75 % voorspeld | fef75_percpredicted_all_c_1 | fef75pp | [[1A visit 1|1A]] [[2A visit 1|2A]] | 18+ | | ||
| FEF25_75 % predicted | FEF25_75 % voorspeld | fef2575_percpredicted_all_c_1 | fef2575pp | [[1A visit 1|1A]] [[2A visit 1|2A]] | 18+ | | | FEF25_75 % predicted | FEF25_75 % voorspeld | fef2575_percpredicted_all_c_1 | fef2575pp | [[1A visit 1|1A]] [[2A visit 1|2A]] | 18+ | | ||
- | | change in FEV1 2A versus 1A (liter per year) | verandering in FEV1 2A versus 1A (liter per jaar) | fev1_change_all_c_1 | dfev1 | [[1A visit 1|1A]] [[2A visit 1|2A]] | 18+ | | + | | change in FEV1 2A versus 1A (liter per year) | verandering in FEV1 2A versus 1A (liter per jaar) | fev1_change_all_c_1 | dfev1 | [[2A visit 1|2A]] | 18+ | |
- | | change in FEV1FVC 2A versus 1A (liter per year) | verandering in FEV1FVC 2A versus 1A (liter per jaar) | fev1fvc_change_all_c_1 | dfev1fvc | [[1A visit 1|1A]] [[2A visit 1|2A]] | 18+ | | + | | change in FEV1FVC 2A versus 1A (liter per year) | verandering in FEV1FVC 2A versus 1A (liter per jaar) | fev1fvc_change_all_c_1 | dfev1fvc | [[2A visit 1|2A]] | 18+ | |
- | | change in FVC 2A versus 1A (liter per year) | verandering in FVC1 2A versus 1A (liter per jaar) | fvc_change_all_c_1 | dfvc | [[1A visit 1|1A]] [[2A visit 1|2A]] | 18+ | | + | | change in FVC 2A versus 1A (liter per year) | verandering in FVC1 2A versus 1A (liter per jaar) | fvc_change_all_c_1 | dfvc | [[2A visit 1|2A]] | 18+ | |
- | | change in FEF75 2A versus 1A (liter per second per year) | verandering in FEF75 2A versus 1A (liter per seconde per jaar) | fef75_change_all_c_1 | dfef75 | [[1A visit 1|1A]] [[2A visit 1|2A]] | 18+ | | + | | change in FEF75 2A versus 1A (liter per second per year) | verandering in FEF75 2A versus 1A (liter per seconde per jaar) | fef75_change_all_c_1 | dfef75 | [[2A visit 1|2A]] | 18+ | |
- | | change in FEF25_75 2A versus 1A (liter per second per year) | verandering in FEF25_75 2A versus 1A (liter per seconde per jaar) | fef2575_change_all_c_1 | dfef2575 | [[1A visit 1|1A]] [[2A visit 1|2A]] | 18+ | | + | | change in FEF25_75 2A versus 1A (liter per second per year) | verandering in FEF25_75 2A versus 1A (liter per seconde per jaar) | fef2575_change_all_c_1 | dfef2575 | [[2A visit 1|2A]] | 18+ | |
- | | difference in body length adults 2A versus 1A | verschil in lichaamslengte volwassenen 2A versus 1A | spirometry_bodylength_all_c_1 | heightdifference_adults | [[1A visit 1|1A]] [[2A visit 1|2A]] | 18+ | | + | | difference in body length adults 2A versus 1A | verschil in lichaamslengte volwassenen 2A versus 1A | spirometry_bodylength_all_c_1 | heightdifference_adults | [[2A visit 1|2A]] | 18+ | |