family_relations
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family_relations [2023/07/11 11:22] simone |
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| The basis of the family relations data within Lifelines consists of information from the municipal registries (Basisregistratie Personen (BRP)). Based on this information, researchers from the [[ugli|UGLI-consortium]] have optimized the family relations using recoded surname data (for privacy purposes) and data from questionnaires ([[family_composition|Family composition]]). The process of this optimization has been documented and can be found here: {{ :lifelines_familyreconstruction.pdf | Family relations reconstruction}}. | The basis of the family relations data within Lifelines consists of information from the municipal registries (Basisregistratie Personen (BRP)). Based on this information, researchers from the [[ugli|UGLI-consortium]] have optimized the family relations using recoded surname data (for privacy purposes) and data from questionnaires ([[family_composition|Family composition]]). The process of this optimization has been documented and can be found here: {{ :lifelines_familyreconstruction.pdf | Family relations reconstruction}}. | ||
| - | These optimized family relations were then verified by the UGLI-consortium using available genetic data. The most recent version of the family relations data (sec_family_relations_v3.1) has been verified by using genetic data from GWAS (CytoSNP), UGLI 1 (GSA), and UGLI 2 (Affymetrix). More detailed information on this process can be found in the quality control document of UGLI2-Affymetrix: QC_report_UGLI2_(release_1)-v1.pdf , page 6 - 9, section 6b and in the readme of the family relations file . | + | These optimized family relations were then verified by the UGLI-consortium using available genetic data. The most recent version of the family relations data (sec_family_relations_v3.1) has been verified by using genetic data from [[gwas|GWAS (CytoSNP)]], [[ugli|UGLI 1 (GSA), and UGLI 2 (Affymetrix)]]. More detailed information on this process can be found in the quality control document of UGLI2-Affymetrix: {{ :QC_report_UGLI2_(release_1)-v1.pdf |QC_report_UGLI2_(release_1)-v1.pdf}}, page 6 - 9, section 6b and in the {{ :readme_family_relations_v3.1.pdf |readme of the familyrelations}}. |
| In the latest version of the family relations data, couples who share a household, but don't have children, have also been included. This provides the opportunity to work on research involving environmental factors. | In the latest version of the family relations data, couples who share a household, but don't have children, have also been included. This provides the opportunity to work on research involving environmental factors. | ||
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| {{::pedigree_concordance_analysis.png?direct&600|}} | {{::pedigree_concordance_analysis.png?direct&600|}} | ||
| - | More detailed information on this process can be found in the quality control document of UGLI2-Affymetrix: {{ :QC_report_UGLI2_(release_1)-v1.pdf |QC_report_UGLI2_(release_1)-v1.pdf}}, page 6 - 9, section 6b. | + | |
family_relations.txt ยท Last modified: 2023/07/11 12:14 by simone
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