family_relations
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family_relations [2023/05/04 13:14] simone |
family_relations [2023/07/11 11:23] simone |
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| ====== Family Relations ====== | ====== Family Relations ====== | ||
| - | The Lifelines cohort consists of a lot of family relationships. During the inclusion participants were asked if they had any family members who would be interested in joining the cohort. As a result of this Lifelines is one of the largest 3 generation cohorts available. | + | The Lifelines cohort consists of many family relationships. During the inclusion into Lifelines, participants were asked if they had any family members who would be interested in joining the cohort. As a result Lifelines is one of the largest 3 generation cohorts available. |
| - | The basis of the family relations data within Lifelines consists of information from the municipal registries (Basisregistratie Personen (BRP)). Based on this information, researchers from the [[ugli|UGLI-consortium]] have optimized the family relations using recoded surname data (for privacy purposes) and data from questionnaires ([[family_composition|Family composition]]). The process of this optimization has been documented and can be found here: {{ :lifelines_familyreconstruction.pdf | Family relations reconstruction}} | + | The basis of the family relations data within Lifelines consists of information from the municipal registries (Basisregistratie Personen (BRP)). Based on this information, researchers from the [[ugli|UGLI-consortium]] have optimized the family relations using recoded surname data (for privacy purposes) and data from questionnaires ([[family_composition|Family composition]]). The process of this optimization has been documented and can be found here: {{ :lifelines_familyreconstruction.pdf | Family relations reconstruction}}. |
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| + | These optimized family relations were then verified by the UGLI-consortium using available genetic data. The most recent version of the family relations data (sec_family_relations_v3.1) has been verified by using genetic data from [[gwas|GWAS (CytoSNP)]], [[ugli|UGLI 1 (GSA), and UGLI 2 (Affymetrix)]]. More detailed information on this process can be found in the quality control document of UGLI2-Affymetrix: QC_report_UGLI2_(release_1)-v1.pdf , page 6 - 9, section 6b and in the readme of the family relations file . | ||
| In the latest version of the family relations data, couples who share a household, but don't have children, have also been included. This provides the opportunity to work on research involving environmental factors. | In the latest version of the family relations data, couples who share a household, but don't have children, have also been included. This provides the opportunity to work on research involving environmental factors. | ||
family_relations.txt · Last modified: 2023/07/11 12:14 by simone
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