Lifelines includes predominantly health-related variables. A large portion of those variables are aimed to assess whether participants have particular diseases and/or (undiagnosed) symptoms, via self-report questionnaires.
Variables that more neutrally assess the (measured and/or self-reported) physical characteristics of participants, independent of specific diseases and symptoms, can be found here.

In Lifelines, variables in this section are organized in the following subsections:

1. Acne
2. Adrenal gland disorders
3. Allergies
4. Blood disorders
5. Bronchial Hyperresponsiveness (BHQ)
6. Cancer
7. Cardiovascular diseases
8. Cardiovascular symptoms
9. Chronic diseases (Covid-19)
10. Cold/Flu
11. Connective Tissue Disease (CSQ)
12. Covid-19 infection
13. Diabetes
14. Digestive system diseases
15. Digestive symptoms
16. Functional bowel symptoms (Rome III)
17. Diseases (other)
18. Diseases (PROMAS)
19. Ear conditions
20. Eye conditions (general)
21. Eye conditions (OQ)
22. Eating disorders
23. Fatigue (general)
24. Fatigue (CDC)
25. Fatigue (PROMIS)
26. Fatigue (CIS)
27. Fever
28. General health (PROMIS)
29. Insomnia
30. Kidney & bladder diseases
31. Menopausal Symptoms (GCS)
32. Mental illnesses
33. Musculoskeletal conditions
34. Musculoskeletal symptoms
35. Musculoskeletal pain (WPI)
36. Neurological disorders
37. Occupational eczema (NOSQ)
38. Oral cavity conditions
39. Ostheoarthritis (WOMAC)
40. Reproductive organ diseases
41. Respiratory diseases
42. Respiratory problems (general)
43. Respiratory problems (ELON)
44. Skin conditions
45. STDs
46. Symptoms (Covid-19)
47. Symptoms (SCL-90)
48. Throat conditions
49. Upper extremities (UEFS)