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deep [2021/01/21 16:40]
sylvia [Genomics]
deep [2023/11/14 12:00] (current)
sylvia [Data availability]
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 ====== DEEP/DAG1 ====== ====== DEEP/DAG1 ======
-Lifelines-DEEP,​ also known as DAG1, is one of [[start|Lifelines]]'​ [[additional assessments]] performed in collaboration with the UMCG [[https://​www.systemsgenetics.nl/​|department of genetics]] (see also: [[DAG2]] and [[DAG3]]). DAG is the abbreviation of DArmGezondheid,​ or "​Gastrointestinal health"​ in Dutch, a research project in which the microbiome is analysed in [[faecal analyses|faecal samples]].\\+Lifelines-DEEP,​ also known as DAG1, is one of [[start|Lifelines]]'​ [[additional assessments]] performed in collaboration with the UMCG [[https://​www.systemsgenetics.nl/​|department of genetics]] (see also: [[DAG2]] and [[DAG3]]). DAG is the abbreviation of DArmGezondheid,​ or "​Gastrointestinal health"​ in Dutch, a research project in which the microbiome is analysed in faecal samples.\\
 The primary goal of the Lifelines-DEEP project is to get insight in the relations between [[https://​en.wikipedia.org/​wiki/​Genome|genome]],​ [[https://​en.wikipedia.org/​wiki/​epigenome|epigenome]],​ [[https://​en.wikipedia.org/​wiki/​Transcriptome|transcriptome]],​ [[https://​en.wikipedia.org/​wiki/​microbiome|microbiome]],​ [[https://​en.wikipedia.org/​wiki/​metabolome|metabolome]],​ and other biological and phenotypic parameters. Lifelines-DEEP is an example of a ‘next- generation’ population cohort study—in which multiple molecular data levels are combined with observational research methods ((Tigchelaar EF et al. (2015) Cohort profile: LifeLines DEEP, a prospective,​ general population cohort study in the northern Netherlands:​ study design and baseline characteristics. BMJ Open 5(8): e006772)) The primary goal of the Lifelines-DEEP project is to get insight in the relations between [[https://​en.wikipedia.org/​wiki/​Genome|genome]],​ [[https://​en.wikipedia.org/​wiki/​epigenome|epigenome]],​ [[https://​en.wikipedia.org/​wiki/​Transcriptome|transcriptome]],​ [[https://​en.wikipedia.org/​wiki/​microbiome|microbiome]],​ [[https://​en.wikipedia.org/​wiki/​metabolome|metabolome]],​ and other biological and phenotypic parameters. Lifelines-DEEP is an example of a ‘next- generation’ population cohort study—in which multiple molecular data levels are combined with observational research methods ((Tigchelaar EF et al. (2015) Cohort profile: LifeLines DEEP, a prospective,​ general population cohort study in the northern Netherlands:​ study design and baseline characteristics. BMJ Open 5(8): e006772))
  
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 ===== Data availability ===== ===== Data availability =====
-^ Type          ^ N          ^ Available? ​ ^ +^ Type                ^ N         ​^ Available? ​ ^ 
-| Genomics ​     | +/- 1400   ​| Yes         | +| Genomics ​(cytosnp)  ​| +/- 1400  | Yes         | 
-| Methylation ​  ​| +/- 800    | Yes         | +| Methylation ​        ​| +/- 800   ​| Yes         | 
-| RNAseq ​       | +/- 1300   ​No          ​+| RNAseq ​             | +/- 1300  Yes         
-| MGS           ​| +/- 1200   ​| Yes*        | +| MGS                 ​| +/- 1200  | Yes*        | 
-| 16S           ​| +/- 1000   ​| Yes*        | +| 16S                 ​| +/- 1000  | Yes*        | 
-| Metabolomics ​ | -          No          ​+| Metabolomics ​       | +/- 1400  ​| ​Yes         | 
-| Proteomics ​   | -          No          ​|+| Cytokines ​          | +/1100  ​Yes         
 +| Proteomics ​         +/1100  ​Yes         | 
 +| WES                 | +/- 1000  | Yes         |
 *Raw data is available; the processed data is not available yet *Raw data is available; the processed data is not available yet
  
deep.1611243624.txt.gz · Last modified: 2021/01/21 16:40 by sylvia